Predictive calue of leucocyte count, neutrophil percent and C-reactive protein concentration “cut-off value” on the diagnosis of appendicitis [Lökosit sayısı, yüzde nötrofil oranı ve C-reaktif protein konsantrasyonlarının “kesim değeri” düzeylerinde apandisit tanısındaki değerleri]

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dc.contributor.authorAyrık C.
dc.contributor.authorKaraaslan U.
dc.contributor.authorDağ A.
dc.contributor.authorBozkurt S.
dc.contributor.authorToker İ.
dc.contributor.authorDemir F.
dc.date.accessioned2019-08-01T13:38:39Z
dc.date.available2019-08-01T13:38:39Z
dc.date.issued2016
dc.departmentNiğde ÖHÜ
dc.description.abstractBACKGROUND: The present study aimed to investigate the predictive importance of cut-off levels of preoperative WBC, neutrophil and CRP concentrations in operated appendicitis patients. METHODS: Patients operated for acute appendicitis between January 2008 and November 2010 were retrospectively screened. Patients were divided into three groups according to postoperative histopathology. Group I: normal appendix, Group II: Uncomplicated appendicitis, Group III: complicated appendicitis. ROC curves are intended for positive distinguishing pathological laboratory measurements. Cut-off values were determined and distinguishing performances were assessed. RESULTS: 175 of the 320 patients were males (54.7%) and 145 were females (45.3%). Average age was 35.95±14.75. While cut-off value for WBC was 12.080 and it was found significant in distinguishing total appandisitis (group II+group III) from normal appendixes and distinguishing group II from group I (p<0.001), it was determined that it was not significant in distinguishing group II from group III (p=0.768). While cut-off value for neutrophil was 73% and it was significant in distinguishing group II+group III from group I and group II from group I (p<0.001), it was detected that it was not significant in distinguishing group II from group III (p=0.681). While cut-off value for CRP was 45.98, it was not found significant in distinguishing group II+group III from group I and group II from group I; however it was significant in distinguishing group II from group III (p<0.001). When all measurements were evaluated together, it was detected that the increase in only the neutrophil percentage rised the non-complicated acute appendisitis (OR: 1.082; p<0.001), and the increase in both neutrophiles and CRP resulted in a rise in the risk of complication (OR: neutrophil= 1.066; p=0.009- CRP=1.005; p=0.013). DISCUSSION: The cut-off value of labaratuary tests may help determine the diagnosis and treatment. Especially, cut-off value of CRP may be helpful to determine the method of incision during the operation as conventional appendectomy or laparoscopic appendectomy. © 2016 TJTES.
dc.identifier.doi10.5505/tjtes.2015.91112
dc.identifier.endpage83
dc.identifier.issn1306696X
dc.identifier.issue1
dc.identifier.pmid27135082
dc.identifier.startpage76
dc.identifier.urihttps://dx.doi.org/10.5505/tjtes.2015.91112
dc.identifier.urihttps://hdl.handle.net/11480/1898
dc.identifier.volume22
dc.indekslendigikaynakPubMed
dc.institutionauthor[0-Belirlenecek]
dc.language.isotr
dc.publisherTurkish Association of Trauma and Emergency Surgery
dc.relation.ispartofUlusal Travma ve Acil Cerrahi Dergisi
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAppendicitis
dc.subjectC-reactive protein
dc.subjectCut-off
dc.subjectLeucocyte
dc.subjectNeutrophil
dc.titlePredictive calue of leucocyte count, neutrophil percent and C-reactive protein concentration “cut-off value” on the diagnosis of appendicitis [Lökosit sayısı, yüzde nötrofil oranı ve C-reaktif protein konsantrasyonlarının “kesim değeri” düzeylerinde apandisit tanısındaki değerleri]
dc.typeArticle

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