Evaluation of the Nasal Olfactory Mucosal Area in Patients Affected by Olfactory Dysfunction Associated with Coronavirus Disease 2019

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dc.contributor.authorAksoy, Ahmet
dc.contributor.authorÇırakoğlu, Mehmet Furkan
dc.contributor.authorBingöl, Fatih
dc.contributor.authorBingöl, Buket Özel
dc.date.accessioned2024-11-07T10:40:17Z
dc.date.available2024-11-07T10:40:17Z
dc.date.issued2023
dc.departmentNiğde Ömer Halisdemir Üniversitesi
dc.description.abstractObjective: While researchers have posited various factors, the precise etiology of anosmia in coronavirus disease 2019 (COVID-19) patients remains elusive. We aimed to investigate the relationship between the status of the nasal olfactory mucosal area and medical and demographic variables in patients with COVID-19-related olfactory dysfunction. Methods: In a retrospective analysis, we scrutinized data from 65 adult COVID-19 patients who exhibited olfactory impairment, excluding those with specific medical histories or age-related criteria. Our assessment comprised the analysis of paranasal sinus computed tomography scans to assess inflammation within the nasal olfactory mucosa. Olfactory testing was not employed in this study. We conducted a comprehensive investigation to explore potential associations with gender, age, septal deviation status, taste disorders, and the timing of the onset of olfactory dysfunction. Results: The average age of the patients was 31.6 ± 12.4 years, with 18 (27.7%) male and 47 (72.3%) female patients. Of 65 patients, 43 (66.2%) reported olfactory dysfunction simultaneously with COVID-19, while 22 (33.8%) experi-enced it after testing positive. Taste abnormalities were present in 49 patients (75.4%). Thirty-seven patients (56.9%) had a nasal septum deviation. Inflammation in the olfactory mucosal region was found in 8 patients (12.3%). The study did not find any significant association between inflammation in the olfactory mucosa and factors like age, gender, taste disorders, or the type of olfactory dysfunction. Still, a significant correlation was found between inflammation in the olfactory mucosal region and nasal septal deviation (P = .009). Conclusion: In COVID-19 patients with olfactory dysfunction, nasal septal deviation was the most common accom-panying factor with olfactory mucosal area inflammation, suggesting it may be a potential risk factor. © Author(s).
dc.identifier.doi10.5152/ejra.2023.23105
dc.identifier.endpage75
dc.identifier.issn2636-8072
dc.identifier.issue3
dc.identifier.scopus2-s2.0-85180677634
dc.identifier.scopusqualityN/A
dc.identifier.startpage72
dc.identifier.urihttps://doi.org/10.5152/ejra.2023.23105
dc.identifier.urihttps://hdl.handle.net/11480/11548
dc.identifier.volume6
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherAVES
dc.relation.ispartofEuropean Journal of Rhinology and Allergy
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241106
dc.subjectanosmia
dc.subjectCOVID-19
dc.subjectolfactory disorder
dc.subjectparanasal sinus computed tomography
dc.subjecttaste disorder
dc.titleEvaluation of the Nasal Olfactory Mucosal Area in Patients Affected by Olfactory Dysfunction Associated with Coronavirus Disease 2019
dc.typeArticle

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