Objective Signs versus Subjective Disease Index in Dry Eye Disease

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dc.contributor.authorTurkoglu, Ceren
dc.date.accessioned2024-11-07T10:40:19Z
dc.date.available2024-11-07T10:40:19Z
dc.date.issued2024
dc.departmentNiğde Ömer Halisdemir Üniversitesi
dc.description.abstractObjective: To compare the ocular surface disease index (OSDI) questionnaire with objective tests in dry eye disease. Study Design: A prospective observational study. Place and Duration of the Study: Department of Ophthalmology, Nigde Omer Halisdemir University, Nigde, Turkiye, from 9th June to 31st December 2022. Methodology: All clinically diagnosed 323 eyes of patients with dry eye disease (DED) were included. The subjects were evaluated by the Oxford classification of corneal and conjunctival fluorescein staining, Schirmer I test, and fluorescein tear breakup time (TBUT). Symptoms of the patients were interpreted with OSDI and correlations of symptoms and objective markers were analysed. Results: There was no significant association between any objective signs (Schirmer I, TBUT, and Oxford), and OSDI (p = 0.26, 0.52, 0.18, and respectively). Schirmer I score showed a significant positive correlation with TBUT (p <0.001, r = 0.21) and a significant negative correlation with Oxford scale (p <0.001, r = -0.19). There was a statistically negative correlation between TBUT and Oxford scale (p <0.001, r = -0.37). Conclusion: Except for the Schirmer test, TBUT and Oxford scale are effective tools in the diagnosis of DED. Symptom markers, such as OSDI may have lower reliability in diagnosing DED and determining its severity. Diagnostic tests are important in the detection of asymptomatic or less severe dry eye disease that can be ignored. © 2024 College of Physicians and Surgeons Pakistan. All rights reserved.
dc.identifier.doi10.29271/jcpsp.2024.07.845
dc.identifier.endpage847
dc.identifier.issn1022-386X
dc.identifier.issue7
dc.identifier.pmid38978253
dc.identifier.scopus2-s2.0-85198312049
dc.identifier.scopusqualityQ3
dc.identifier.startpage845
dc.identifier.urihttps://doi.org/10.29271/jcpsp.2024.07.845
dc.identifier.urihttps://hdl.handle.net/11480/11584
dc.identifier.volume34
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherCollege of Physicians and Surgeons Pakistan
dc.relation.ispartofJournal of the College of Physicians and Surgeons Pakistan
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241106
dc.subjectDiagnosis
dc.subjectDry eye disease
dc.subjectOcular surface disease index (OSDI)
dc.subjectOxford grading scale
dc.subjectSchirmer I test
dc.subjectTear breakup time (TBUT)
dc.titleObjective Signs versus Subjective Disease Index in Dry Eye Disease
dc.typeArticle

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