Evaluation of subclinical left ventricular systolic dysfunction in patients with obstructive sleep apnea by automated function imaging method; an observational study [Obstrüktif uyku apneli hastalarda subklinik sol ventrikül sistolik disfonksiyonunun otomatik fonksiyonel görüntüleme yöntemiyle degerlendirilmesi: Gözlemsel bir çali{dotless}şma]

Basit Öğe Kaydı
dc.contributor.authorAltekin Dr. R.E.
dc.contributor.authorYanikoglu A.
dc.contributor.authorKarakaş M.S.
dc.contributor.authorÖze D.
dc.contributor.authorYildirim A.B.
dc.contributor.authorKabukçu M.
dc.date.accessioned2019-08-01T13:38:39Z
dc.date.available2019-08-01T13:38:39Z
dc.date.issued2012
dc.departmentNiğde ÖHÜ
dc.description.abstractObjective: We aimed to evaluate the subclinical left ventricular (LV) systolic dysfunction with the automated function imaging method (AFI) based on speckle tracking echocardiography (STE) in obstructive sleep apnea patients (OSA) with normal left ventricular ejection fraction (LVEF) and without any confounding disease that can cause myocardial dysfunction. Methods: Twenty-one healthy individuals and 58 OSA patients were included in this observational cross-sectional study. According to the severity of disease, OSA patients were examined in three groups; mild, moderate and severe OSA. Apical 2-, 3- and 4- chamber images were obtained for AFI evaluation. The global systolic longitudinal strain (GL S) values were determined for each view, and averages of these were used in comparison of the patient groups. One-way ANOVA, Kruskal-Wallis, Pearson correlation tests and linear regression analysis were used for statistical analysis. Results: The GL S values of the OSA patients were lower than of the healthy individuals and these values were decreased along with the OSA severity (Healthy:-25.58±-2.16%, Mild:-23.93±-3.96%, Moderate:-21.27±-2.60%, Severe:-16.94±-2.66%, respectively). The difference was significant between moderate OSA patients and healthy individuals, and significant between severe OSA patients and all other groups (p<0.03). The apnea-hypopnea index was found to be correlated with the GL S (ß=-0.659, 95% CI: 0.09-0.17, p<0.001). Conclusion: Longitudinal LV mechanics in OSA patients with normal LVEF are deteriorated in the subclinical stage being associated with the severity of disease. AFI can be used as an effective and safe method in the determination of subclinical myocardial dysfunction in OSA patients, because it is semi-automated and easy to use with a short analysis time. © Copyright 2012 by AVES Yayi{dotless}nci{dotless}li{dotless}k Ltd.
dc.identifier.doi10.5152/akd.2012.096
dc.identifier.endpage330
dc.identifier.issn1302-8723
dc.identifier.issue4
dc.identifier.pmid22466365
dc.identifier.startpage320
dc.identifier.urihttps://dx.doi.org/10.5152/akd.2012.096
dc.identifier.urihttps://hdl.handle.net/11480/903
dc.identifier.volume12
dc.indekslendigikaynakPubMed
dc.institutionauthor[0-Belirlenecek]
dc.language.isoen
dc.relation.ispartofAnadolu Kardiyoloji Dergisi
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectMyocardial strain
dc.subjectObstructive sleep apnea
dc.subjectRegression analysis
dc.subjectSpeckle tracking echocardiography
dc.titleEvaluation of subclinical left ventricular systolic dysfunction in patients with obstructive sleep apnea by automated function imaging method; an observational study [Obstrüktif uyku apneli hastalarda subklinik sol ventrikül sistolik disfonksiyonunun otomatik fonksiyonel görüntüleme yöntemiyle degerlendirilmesi: Gözlemsel bir çali{dotless}şma]
dc.typeArticle

Dosyalar

Koleksiyon

Scopus İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu