Mechanisms and grading of nocturia: Results from a multicentre prospective study

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dc.authoridErbatu, Oguzcan/0000-0002-2840-0028
dc.authoridOzdemir, Turan/0000-0002-1131-2507
dc.authoridCihan, Ahmet/0000-0001-5586-8673
dc.authoridIrer, Bora/0000-0002-7719-9033
dc.authoridSen, Volkan/0000-0003-2832-0682
dc.contributor.authorBozkurt, Ozan
dc.contributor.authorIrer, Bora
dc.contributor.authorKizilay, Fuat
dc.contributor.authorErbatu, Oguzcan
dc.contributor.authorSen, Volkan
dc.contributor.authorCinar, Onder
dc.contributor.authorOngun, Sakir
dc.date.accessioned2024-11-07T13:35:25Z
dc.date.available2024-11-07T13:35:25Z
dc.date.issued2021
dc.departmentNiğde Ömer Halisdemir Üniversitesi
dc.description.abstractObjective To identify the pathophysiological mechanisms of nocturia and the correlation of these mechanisms with nocturia severity. Methodology After approval by the local ethics committee, all patients with nocturia (>= 1 nocturnal void/night) were included and filled the Overactive Bladder questionnaire, Nocturia Quality of Life, Incontinence Questionnaire - Male Lower Urinary Tract Symptoms (male), International Consultation on Incontinence Questionnaire - Female Lower Urinary Tract Symptoms (female) and 3-day frequency-volume chart. Patients were divided into three groups according to the severity of nocturia: group 1 consisted of patients with mild (1-2 voids/night), group 2 with moderate (3-4 voids/night) and group 3 with severe nocturia (>4 voids/night). Comparative analysis was performed between groups, andP About 68.1%, 64.1% and 8.7% of the patients had nocturnal polyuria (NP), reduced bladder capacity and global polyuria, respectively. 42.7% of the patients had mixed nocturia. 6.1% of the patients did not comply with the aforementioned subtypes and defined as isolated nocturia. Regarding the severity of nocturia, 155 (41%) patients had mild, 167 (45%) patients had moderate and 57 (15%) patients had severe nocturia. Increased nocturia severity was related with decreased quality of life; higher age, urinary tract symptom scores, nocturnal urine volume, evening fluid consumption and beta-blocker medication rates. Increased nocturia severity was also associated with higher NP, global polyuria and reduced bladder capacity rates. Conclusions Nocturia mechanisms may vary between mild and moderate to severe nocturia groups according to the present study. Nocturia grading with identification of subtypes may help for better standardisation of the diagnostic and treatment approaches as well as for the design of future clinical trials.
dc.identifier.doi10.1111/ijcp.13722
dc.identifier.issn1368-5031
dc.identifier.issn1742-1241
dc.identifier.issue3
dc.identifier.pmid32969572
dc.identifier.scopus2-s2.0-85092490414
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org/10.1111/ijcp.13722
dc.identifier.urihttps://hdl.handle.net/11480/16491
dc.identifier.volume75
dc.identifier.wosWOS:000578744300001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherWiley
dc.relation.ispartofInternational Journal of Clinical Practice
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241106
dc.subjectQuality-Of-Life
dc.subjectUrinary-Tract Symptoms
dc.subjectAssociation
dc.subjectPrevalence
dc.subjectAdults
dc.subjectQuestionnaire
dc.subjectEtiology
dc.subjectMen
dc.subjectAge
dc.titleMechanisms and grading of nocturia: Results from a multicentre prospective study
dc.typeArticle

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