Sonographic evaluation of subclinical entheseal involvement in patients with hypoparathyroidism: a case control study

Basit Öğe Kaydı
dc.authoridOmma, Tulay/0000-0002-2557-9499
dc.authoridFirat, Sevde nur/0000-0001-9386-5879
dc.authoridOnder, Cagatay Emir/0000-0002-0293-2309
dc.authoridGenc, Hakan/0000-0003-2573-4564
dc.contributor.authorFirat, S. N.
dc.contributor.authorKuskonmaz, S. M.
dc.contributor.authorOnder, C. E.
dc.contributor.authorOmma, T.
dc.contributor.authorGenc, H.
dc.contributor.authorCulha, C.
dc.date.accessioned2024-11-07T13:32:12Z
dc.date.available2024-11-07T13:32:12Z
dc.date.issued2023
dc.departmentNiğde Ömer Halisdemir Üniversitesi
dc.description.abstractPurpose Hypoparathyroidism is a disease characterized by low serum calcium, increased serum phosphorus and low PTH levels. Although patients are treated with active vitamin D and calcium, a proper serum calcium phosphorus balance cannot always be achieved. Ectopic calcifications that develop in organs during treatment are the most common complications. To date, there is not any published study on enthesopathy in patients with hypoparathyroidism. The aim of this study was to evaluate subclinical enthesopathy in patients with hypoparathyroidism with ultrasound and to compare the results with those of the control group. Methods The study included patients aged 18-65 years with postoperative hypoparathyroidism and hypothyroidism (group hypoP + hypoT), patients with postoperative hypothyroidism (group hypoT), and healthy age and sex-matched volunteers (group C). Ultrasonographic findings of enthesopathy in both extremities were documented according to the Glasgow Ultrasound Enthesitis Scoring System (GUESS). Results GUESS scores in group hypoP + hypoT, were significantly higher when compared to the other groups. There was a statistically significant correlation between the total GUESS scores and total enthesophyte scores and the duration of hypoparathyroidism (p < 0.05, r = 0.43) (p < 0.05, r = 0.39) respectively. In the correlation analysis of all groups, a significant negative correlation was found between serum Ca and PTH levels and the total GUESS scores (p < 0.01, r = - 0.37; p < 0.01, r = - 0.54, respectively). Conclusion This study showed that GUESS scores were significantly higher in patients with hypoparathyroidism compared to those with hypothyroidism and control subjects. GUESS scores were positively correlated with disease duration. Patients with hypoparathyroidism need to be evaluated for subclinical enthesopathy during follow-up.
dc.identifier.doi10.1007/s40618-022-01891-7
dc.identifier.endpage139
dc.identifier.issn0391-4097
dc.identifier.issn1720-8386
dc.identifier.issue1
dc.identifier.pmid35982371
dc.identifier.scopus2-s2.0-85136257335
dc.identifier.scopusqualityQ2
dc.identifier.startpage133
dc.identifier.urihttps://doi.org/10.1007/s40618-022-01891-7
dc.identifier.urihttps://hdl.handle.net/11480/15267
dc.identifier.volume46
dc.identifier.wosWOS:000841688200001
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringer
dc.relation.ispartofJournal of Endocrinological Investigation
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241106
dc.subjectEnthesopathy
dc.subjectHypoparathyroidism
dc.subjectGlasgow Ultrasound Enthesitis Scoring System
dc.titleSonographic evaluation of subclinical entheseal involvement in patients with hypoparathyroidism: a case control study
dc.typeArticle

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu