Relationship between echocardiography and arterial stiffness parameters and chorodial thickness in healthy subjects
Küçük Resim Yok
Tarih
2022
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Edizioni Minerva Medica
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
ABSTR A C T BACKGROUND: Choroid is one of the most vascularized tissues of the body. Enhanced depth imaging optical coher-ence tomography (EDI-OCT) is the diagnostic method for choroid imaging. An increase in arterial stiffness, one of the important determinants of vascular aging, is a prognostic predictor of cardiovascular mortality. Carotid-femoral pulse wave velocity (CFPWV) is the gold standard method for the detection of arterial stiffness and has a high predictive value for undesirable cardiovascular events. The aim of our study was to investigate whether there is a relationship between choroidal thickness and echocardiographic findings, CFPWV, arterial stiffness, aortic distensibility and other basic pa-rameters in healthy middle-aged subjects. METHODS: The study included 80 healthy individuals aged 30-60 years. Firstly, echocardiographic and arterial stiffness levels of volunteers were evaluated, and choroidal thickness was determined by EDI-OCT. The relationship between choroidal thickness and other parameters was evaluated by Pearson correlation test. RESULTS: A total of 80 healthy volunteers (35 females, 43%) were included in the study. The mean age was 42.40-17.68 years (range, 31-60 years). It was found that there were a negative correlation between choroid and age (r=-0.80, P<0.01), left ventricular deceleration time (r=-0.72, P<0.01), isovolumic relaxation time (r=-0.76, P<0.01), ee (r =-0.68, P<0.01), annular late diastolic velocity (r=-0.25, P<0.05), CFPWV (r=-0.70, P<0.01) and aortic stiffness (r=-0.76, P<0.01). There was a significant positive correlation between choroid and aortic distensibility (r=0.81, P<0.01). There was no difference between the genders in terms of choroidal thickness (t[77]=0.47, P>0.05). CONCLUSIONS: Correlation between advanced age, left ventricular diastolic dysfunction, increased arterial stiffness parameters, decreased aortic distensibility and choroidal thinning were observed.
Açıklama
Anahtar Kelimeler
Vascular stiffness, Carotid-femoral pulse wave velocity, Echocardiography
Kaynak
Gazzetta Medica Italiana Archivio Per Le Scienze Mediche
WoS Q Değeri
N/A
Scopus Q Değeri
Q4
Cilt
181
Sayı
3
