New biobased non-ionic hyperbranched polymers as environmentally friendly antibacterial additives for biopolymers

Basit Öğe Kaydı
dc.authoridZhang, Baozhong/0000-0002-7308-1572
dc.authoridIlk, Sedef/0000-0002-6754-792X
dc.contributor.authorArza, Carlos R.
dc.contributor.authorIlk, Sedef
dc.contributor.authorDemircan, Deniz
dc.contributor.authorZhang, Baozhong
dc.date.accessioned2024-11-07T13:31:42Z
dc.date.available2024-11-07T13:31:42Z
dc.date.issued2018
dc.departmentNiğde Ömer Halisdemir Üniversitesi
dc.description.abstractThe aim of this research was to develop new biobased non-ionic polymeric additives with significant bacterial inhibition and low leaching potential, so that they can be used to produce biopolymer materials for various applications such as biomedical devices, surgical textile, or food packaging. Two new non-ionic hyperbranched polymers (HBPs) were prepared by a facile solvent-free polymerization of an AB2monomer derived from naturally existing molecular building blocks 2-phenylethanol, isatin, and anisole. The molecular structures and thermal properties of the obtained HBPs were characterized by GPC, NMR, FTIR, HRMS, MALDI-TOF, TGA and DSC analyses. Disk diffusion tests revealed that the two obtained HBPs showed more significant antibacterial activity against 9 different food and human pathogenic bacteria, compared with small molecular antibiotics. The maximal antibacterial effect of HBPs was achieved at 2 ae g per disk (or 0.1 mg mL-1), which was significantly lower (similar to 1/15) compared to the linear antibacterial polymer chitosan. Such enhanced antibacterial properties can be attributed to the unique highly branched structures and effectively amplified functionalities of HBPs. Finally, the prepared HBPs were added into natural polymers cellulose and polyhydroxybutyrate (PHB), and the resulting biopolymer films showed no significant leakage after being merged in water for 5 days. This was in sharp contrast to the biopolymer films containing a small model compound, which leaked out significantly under the same conditions. To our knowledge, this is the first report on non-ionic bio-based dendritic macromolecules with significant bacteria inhibition and low leakage.
dc.description.sponsorshipAForsk Foundation [16-479]; Crafoord Foundation [20160774]; Royal Physiographic Society in Lund
dc.description.sponsorshipThis research was financially supported by the AForsk Foundation (No. 16-479), the Crafoord Foundation (No. 20160774), and the Royal Physiographic Society in Lund. We thank Sofia Essen and Katja Bernfur for the help in mass spectrometry.
dc.identifier.doi10.1039/c7gc03401f
dc.identifier.endpage1249
dc.identifier.issn1463-9262
dc.identifier.issn1463-9270
dc.identifier.issue6
dc.identifier.scopus2-s2.0-85044214073
dc.identifier.scopusqualityQ1
dc.identifier.startpage1238
dc.identifier.urihttps://doi.org/10.1039/c7gc03401f
dc.identifier.urihttps://hdl.handle.net/11480/14987
dc.identifier.volume20
dc.identifier.wosWOS:000428088400011
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherRoyal Soc Chemistry
dc.relation.ispartofGreen Chemistry
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241106
dc.subjectOne-Step Synthesis
dc.subjectAntimicrobial Activity
dc.subjectMechanical-Properties
dc.subjectWater Disinfection
dc.subjectPoly(Lactic Acid)
dc.subjectAgents
dc.subjectDendrimers
dc.subjectChemistry
dc.subjectDesign
dc.subjectNanocomposites
dc.titleNew biobased non-ionic hyperbranched polymers as environmentally friendly antibacterial additives for biopolymers
dc.typeArticle

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu