Evaluation of the predictive role of standard laboratory tests for disease severity in patients with deep venous thrombosis

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dc.contributor.authorEtli, Mustafa
dc.contributor.authorKarahan, Oguz
dc.contributor.authorSerhatlioglu, Faruk
dc.contributor.authorOntas, Hakan
dc.date.accessioned2024-11-07T13:32:50Z
dc.date.available2024-11-07T13:32:50Z
dc.date.issued2022
dc.departmentNiğde Ömer Halisdemir Üniversitesi
dc.description.abstractIntroduction: Deep venous thrombosis (DVT) can result in fatal outcomes if it is not timely diagnosed and sufficiently treated. Some laboratory markers were identified in previous reports for predicting the disease with low sensitivity or specificity. We aimed to evaluate the predictive value of serum albumin levels and compare them with conventional laboratory parameters. Material and methods: Fifty patients with acute lower-extremity DVT who has no previous history of malignancy or hematologic disorder were included in the study. The demographical variables and standard biomarkers of the DVT group were compared with the normal population (n:50). Thereafter patients were divided into two groups extensive DVT (thrombosis involves popliteal, femoral, and iliac veins together) and localized DVT (thrombosis involves popliteal vein and below) and biomarkers were compared in patient groups. Results: The demographical variables and white blood cell count (WBC) were found as similar between healthy groups and DVT groups. However, mean platelet volume (MPV), D-Dimer, neutrophil to lymphocyte ratio (NLR), and fibrinogen to albumin ratio (FAR) were found markedly higher in DVT patients. Moreover, statistically incremental FAR and NLR levels were detected (p < 0.05) in patients with extensive DVT (involved iliac and femoral veins). Conclusion: Serum NLR and FAR levels seem to be significant predictors for the extensive thrombotic event in patients with DVT.
dc.identifier.doi10.5603/AA.2022.0001
dc.identifier.endpage21
dc.identifier.issn1234-950X
dc.identifier.issn1644-3276
dc.identifier.issue1
dc.identifier.scopus2-s2.0-85130030619
dc.identifier.scopusqualityQ4
dc.identifier.startpage16
dc.identifier.urihttps://doi.org/10.5603/AA.2022.0001
dc.identifier.urihttps://hdl.handle.net/11480/15639
dc.identifier.volume28
dc.identifier.wosWOS:000794998100001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherVia Medica
dc.relation.ispartofActa Angiologica
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241106
dc.subjectdeep venous thrombosis
dc.subjectextensive disease
dc.subjectneutrophil to lymphocyte ratio
dc.subjectfibrinogen to albumin ratio
dc.titleEvaluation of the predictive role of standard laboratory tests for disease severity in patients with deep venous thrombosis
dc.typeArticle

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