Repeated use of fibrin sealants kept at room temperature in conjunctival autografting: An animal study

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dc.authoridCINAROGLU, Selim/0000-0002-4495-6106
dc.contributor.authorZor, Kursad Ramazan
dc.contributor.authorCinaroglu, Selim
dc.contributor.authorKucuk, Erkut
dc.contributor.authorKeles, Haci
dc.contributor.authorOzturk, Ali
dc.date.accessioned2024-11-07T13:25:21Z
dc.date.available2024-11-07T13:25:21Z
dc.date.issued2022
dc.departmentNiğde Ömer Halisdemir Üniversitesi
dc.description.abstractPurpose: In this study, our aim was to investigate if fibrin adhesives used in conjunctival wound surgery with autologous conjunctival grafts could be used repeatedly at different times after surgical opening. Methods: 40 New Zealand rabbits were used in the study. These animals were divided into four groups, each consisting of 10 rabbits, and hence 20 eyes. In the first group (control group), Tisseel fibrin sealant was used on the day the eye was first opened surgically; in the second group, it was used on the seventh day; on the third group, it was used on the 14th day; and in the fourth group, it was used 28 days after surgical opening. The graft from the inferior bulbar conjunctiva was attached using Tisseel fibrin glue to the superior scleral bed at the location where the superior bulbar conjunctiva was excised in the same eye. Results: No microbial growth was detected in the cultures of the samples tested. There were two partial graft loss in group 2 and there was one partial graft loss in each group of the other groups, and further total graft loss was present in one rabbit in group 3. None of the rabbits had any complications like granuloma, Corneal dellen or infection. Conclusion: Based on these results, fibrin sealants can be used repeatedly by storing them at room temperature. Repeated use of fibrin adhesives will reduce the cost of ophthalmologic surgeries and non-ophthalmologic surgeries.
dc.identifier.doi10.4103/ijo.IJO_2588_21
dc.identifier.endpage1974
dc.identifier.issn0301-4738
dc.identifier.issn1998-3689
dc.identifier.issue6
dc.identifier.pmid35647964
dc.identifier.scopus2-s2.0-85131217143
dc.identifier.scopusqualityQ2
dc.identifier.startpage1971
dc.identifier.urihttps://doi.org/10.4103/ijo.IJO_2588_21
dc.identifier.urihttps://hdl.handle.net/11480/14656
dc.identifier.volume70
dc.identifier.wosWOS:000832280100017
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherWolters Kluwer Medknow Publications
dc.relation.ispartofIndian Journal of Ophthalmology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241106
dc.subjectBulbar conjunctiva
dc.subjectconjunctiva
dc.subjectconjunctival autografting
dc.subjectfibrin sealants
dc.subjectpterygium
dc.titleRepeated use of fibrin sealants kept at room temperature in conjunctival autografting: An animal study
dc.typeArticle

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