Role of propolis on biochemical parameters in kidney and heart tissues against L-NAME induced oxidative injury in rats

Basit Öğe Kaydı
dc.authorid0000-0002-8006-2054
dc.authorid0000-0001-5755-3560
dc.contributor.authorTalas, Zeliha Selamoglu
dc.contributor.authorOzdemir, Ilknur
dc.contributor.authorCiftci, Osman
dc.contributor.authorCakir, Oguz
dc.contributor.authorGulhan, Mehmet Fuat
dc.contributor.authorPasaoglu, Oguz Murat
dc.date.accessioned2019-08-01T13:38:39Z
dc.date.available2019-08-01T13:38:39Z
dc.date.issued2014
dc.departmentNiğde ÖHÜ
dc.description.abstractNitric oxide (NO), produced by endothelial NO synthase, is recognised as a central antiinflammatory and antiatherogenic principle in the vasculature. Epidemiological and clinical studies have demonstrated that a growing list of natural products, as components of the daily diet or phytomedical preparations, may improve vascular function by enhancing NO bioavailability. In this article, we investigated antioxidant effects of propolis on biochemical parameters in kidney and heart tissues of acute NO synthase inhibited rats by N-omega-nitro-L-arginine methyl ester (L-NAME). There was increase (p < 0.001) in the activities of catalase and malondialdehyde levels in the L-NAME treatment groups when compared with control rats, but NO levels were decreased in both kidney and heart tissues. There were statistically significant changes (p < 0.001) in these parameters of L-NAME + propolis treated rats as compared with L-NAME-treated group. In summary, propolis may influence endothelial NO production.
dc.description.sponsorshipNigde University Research Fund [BAP 2008/25]
dc.description.sponsorshipThe authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper. Nigde University Research Fund (BAP 2008/25) is gratefully acknowledged for support of this work.
dc.identifier.doi10.3109/10641963.2013.863322
dc.identifier.endpage496
dc.identifier.issn1064-1963
dc.identifier.issn1525-6006
dc.identifier.issue7
dc.identifier.pmid24490594
dc.identifier.scopus2-s2.0-84908280844
dc.identifier.scopusqualityQ3
dc.identifier.startpage492
dc.identifier.urihttps://dx.doi.org/10.3109/10641963.2013.863322
dc.identifier.urihttps://hdl.handle.net/11480/4229
dc.identifier.volume36
dc.identifier.wosWOS:000344603300009
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthor[0-Belirlenecek]
dc.language.isoen
dc.publisherINFORMA HEALTHCARE
dc.relation.ispartofCLINICAL AND EXPERIMENTAL HYPERTENSION
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectCatalase
dc.subjectL-NAME
dc.subjectmalondialdehyde
dc.subjectnitric oxide
dc.subjectpropolis
dc.subjectrat
dc.titleRole of propolis on biochemical parameters in kidney and heart tissues against L-NAME induced oxidative injury in rats
dc.typeArticle

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