Analysis of pupillary responses in pediatric patients with vitamin D deficiency

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dc.authoridYILMAZ OZTORUN, Zeynep/0000-0001-8017-3048
dc.contributor.authorBicer, Gamze Yildirim
dc.contributor.authorOztorun, Zeynep Yilmaz
dc.contributor.authorBicer, Kadir Eren
dc.contributor.authorZor, Kursad Ramazan
dc.date.accessioned2024-11-07T13:31:32Z
dc.date.available2024-11-07T13:31:32Z
dc.date.issued2024
dc.departmentNiğde Ömer Halisdemir Üniversitesi
dc.description.abstractPurpose To evaluate the effects of vitamin D deficiency on pupillary responses in the pediatric population. Methods The study was conducted using data from the right eyes of 52 children with vitamin D deficiency and 52 healthy children. Measurements were taken under static and dynamic conditions with automatic pupillometry. Static measurements were performed at scotopic, mesopic, and photopic light intensities. The mean pupil dilation speed was calculated by observing the changes in pupil dilation over time according to dynamic measurements. Differences between patient and control groups were analyzed for the static and dynamic measurements and the mean pupil dilation speed. Results While the two groups were similar in terms of scotopic, mesopic, the first dynamic measurements, and the pupil dilation speed data (p > 0.05), a significant difference was found in the photopic conditions (p = 0.001). The mean pupil diameter of the patient group was 4.46 +/- 0.928 mm and 3.95 +/- 0.556 mm in the control group under photopic conditions. Conclusions Pediatric patients with vitamin D deficiency have significantly larger pupil diameters in photopic conditions than healthy children. These results suggest that there is an autonomic dysfunction in vitamin D deficiency in the pediatric population, especially pointing to the parasympathetic system.
dc.identifier.doi10.1007/s00417-024-06428-7
dc.identifier.endpage2632
dc.identifier.issn0721-832X
dc.identifier.issn1435-702X
dc.identifier.issue8
dc.identifier.pmid38416236
dc.identifier.scopus2-s2.0-85186251391
dc.identifier.scopusqualityQ1
dc.identifier.startpage2625
dc.identifier.urihttps://doi.org/10.1007/s00417-024-06428-7
dc.identifier.urihttps://hdl.handle.net/11480/14908
dc.identifier.volume262
dc.identifier.wosWOS:001173222600003
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringer
dc.relation.ispartofGraefes Archive For Clinical and Experimental Ophthalmology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241106
dc.subjectAutomatic pupillometry
dc.subjectAutonomic nervous system
dc.subjectPupil dilation speed
dc.subjectPupillary functions
dc.subjectVitamin D deficiency
dc.titleAnalysis of pupillary responses in pediatric patients with vitamin D deficiency
dc.typeArticle

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