Hepatitis A, B, C and HIV seroprevalence among syrian refugee children admitted to outpatient clinics

dc.contributor.authorKöse, Şükran
dc.contributor.authorÖdemiş, İlker
dc.contributor.authorÇelik, Didem
dc.contributor.authorTatar, Bengü Gireniz
dc.contributor.authorAkbulut, İlkay
dc.contributor.authorÇiftdoğan, Dilek Yılmaz
dc.date.accessioned2024-11-07T10:39:47Z
dc.date.available2024-11-07T10:39:47Z
dc.date.issued2017
dc.departmentNiğde Ömer Halisdemir Üniversitesi
dc.description.abstractViral hepatitis is the most common cause of serious health problems such as liver cirrhosis and hepatocellular carcinoma (HCC). Leading to immunodeficiency disorders through different mechanisms, Human Immunodeficiency Virus (HIV) causes the development of severe secondary infections. Hepatitis A (HAV) is thought to spread by the faecal-oral route, while Hepatitis B (HBV), Hepatitis C (HCV) and HIV are mostly transmitted vertically during childhood. In our study, we aimed to determine the seroprevalence of HAV, HBV, HCV and HIV among Syrian refugee children who were admitted to outpatient clinics. We conducted a retrospective review of data concerning 171 Syrian children aged between 0-18 years admitted between April 2014 and December 2015 to the outpatient infectious disease clinic of İzmir Tepecik Training and Research Hospital and the social welfare outpatient clinic for Syrian refugees for reasons other than jaundice. Serum samples from patients were studied for HAV antibody IgG (anti-HAV IgG), HBV surface antigen (HBsAg), antibodies against HBV surface antigen (anti-HBs), antibodies against HBV core antigen (anti-HBc total), HCV antibody (anti-HCV) (anti- HIV) with the ELISA (Enzyme-Linked Immunosorbent Assay) method. In this study 51% of patients were female, with a mean age of 6.52 years among all patients. Six of the 140 patients (4.2%) scanned for HBV among the patients enrolled in the study were HBsAg and anti-HBc total positive and anti-HBs negative. Three patients (2.1%) were HBsAg negative, and anti-HBc total and anti-HBs positive, which indicated they had previously recovered from an HBV infection. HBsAg, anti-HBs, anti-HBc total data for 140 patients (81.9%), anti-HCV data for 109 patients (63.8%), anti-HIV data for 88 patients (51.5%) and HAV IgG data for 86 patients (50.3%) were obtained. Due to migration from regions in Syria where there is no regular follow-up of HBV vaccination in children, HBsAg seroprevalence of refugee children is thought to be higher than in other children in Turkey and anti-HBs positivity is thought to be lower. We expected to see a higher seroprevalence of anti-HCV and anti-HIV in Syria due to the lack of health facilities such as non-regular anti-HCV and anti-HIV screening before blood transfusions and during pregnancy in all regions of Syria. Yet in this study, the anti-HCV, anti-HIV seroprevalence of Syrian refugee children was similar to that in Turkey. According to the results, if the children of asylum seekers are admitted to the national HAV and HBV vaccination schedule, hepatitis infections and their complications may be prevented. © 2017, EDIMES Edizioni Medico Scientifiche. All rights reserved.
dc.identifier.endpage343
dc.identifier.issn1124-9390
dc.identifier.issue4
dc.identifier.pmid29286012
dc.identifier.scopus2-s2.0-85039912240
dc.identifier.scopusqualityQ2
dc.identifier.startpage339
dc.identifier.urihttps://hdl.handle.net/11480/11206
dc.identifier.volume25
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherEDIMES Edizioni Medico Scientifiche
dc.relation.ispartofInfezioni in Medicina
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241106
dc.subjectHepatitis A
dc.subjectHepatitis B
dc.subjectHepatitis C
dc.subjectHIV
dc.subjectRefugee children
dc.titleHepatitis A, B, C and HIV seroprevalence among syrian refugee children admitted to outpatient clinics
dc.typeArticle

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