Seroprevalence of measles, mumps, rubella, and varicella zoster virus antibodies among healthcare students: analysis of vaccine efficacy and cost-effectiveness

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dc.authoridAlbayrak Ucak, Hazal/0000-0002-8001-0799
dc.authoridodemis, ilker/0000-0003-2638-0163
dc.authoridakbulut, ilkay/0000-0002-4840-6865
dc.contributor.authorOdemis, Ilker
dc.contributor.authorKose, Sukran
dc.contributor.authorAkbulut, Ilkay
dc.contributor.authorAlbayrak, Hazal
dc.date.accessioned2024-11-07T13:34:27Z
dc.date.available2024-11-07T13:34:27Z
dc.date.issued2019
dc.departmentNiğde Ömer Halisdemir Üniversitesi
dc.description.abstractIntroduction. The aims of this study are to determine the seroprevalence for measles, mumps, rubella, and varicella zoster virus (VZV) in a cohort of nursing students, to evaluate vaccination response rates of nonimmune students, and to calculate the cost of vaccinating students based on seroprevalence screening. Material and methods. A cross-sectional study was conducted August 2015-November 2016 among 326 healthy nursing students aged 14.1-18.1 years. Serum IgG antibodies were measured by ELISA. Results were analyzed by the Chi-square test; a p-value of < 0.05 was considered statistically significant. Results. The number of seropositive participants (%) was 308 (94.5%) for rubella, 295 (90.5%) for VZV, 244 (74.9%) for measles, and 219 (67.2%) for mumps. A significant correlation was found between measles IgG and age. A relationship was also observed between VZV IgG and kindergarten attendance. Response rates to measles, rubella, VZV, and mumps vaccination were 96%, 92.3%, 87.5%, 78.8%, respectively. The total cost of vaccination after IgG screening was less than vaccination without screening. Conclusions. In this study, participants' immunity to measles and VZV was low. Prevaccination serological screening was cost-effectiveness method for preventing measles, mumps, rubella, and varicella infections. We believe that administering booster measles, mumps, and rubella (MMR) vaccine doses or developing a special MMR vaccination strategy for at-risk groups may prevent MMR outbreaks.
dc.identifier.endpage531
dc.identifier.issn0214-3429
dc.identifier.issn1988-9518
dc.identifier.issue6
dc.identifier.pmid31642641
dc.identifier.scopus2-s2.0-85076584981
dc.identifier.scopusqualityQ3
dc.identifier.startpage525
dc.identifier.urihttps://hdl.handle.net/11480/15973
dc.identifier.volume32
dc.identifier.wosWOS:000510466200004
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSociedad Espanola Quimioterapia
dc.relation.ispartofRevista Espanola De Quimioterapia
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241106
dc.subjectMeasles
dc.subjectmumps
dc.subjectrubella
dc.subjectvaricella
dc.subjectseroprevalence
dc.subjectvaccine
dc.subjectcost-effectiveness
dc.titleSeroprevalence of measles, mumps, rubella, and varicella zoster virus antibodies among healthcare students: analysis of vaccine efficacy and cost-effectiveness
dc.title.alternativeSeroprevalencia de anticuerpos contra el sarampión, las paperas, la rubéola y el virus de la varicela zoster entre estudiantes de enfermería: Análisis de coste-efectividad de la vacuna
dc.typeArticle

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