Can neutrophil-to-lymphocyte, platelet-to-lymphocyte and monocyte-to-lymphocyte ratios be useful to the diagnosis of aseptic loosening after total knee arthroplasty?

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dc.contributor.authorBozgeyik, B.
dc.contributor.authorTekin, S.B.
dc.contributor.authorMert, A.
dc.date.accessioned2024-11-07T10:39:35Z
dc.date.available2024-11-07T10:39:35Z
dc.date.issued2021
dc.departmentNiğde Ömer Halisdemir Üniversitesi
dc.description.abstractBACKGROUND: The aim of this study is to determine the role of hematological parameters – neutrophil/ lymphocyte, platelet/lymphocyte, and monocyte/lymphocyte ratios – in the diagnosis of aseptic loosening after total knee arthroplasty. METHODS: This study retrospectively analyzed the data of 244 patients who had primary total knee arthroplasty and 66 patients with aseptic loosening developed after total knee arthroplasty. The white blood cell counts, neutrophil/lymphocyte ratio, platelet/lymphocyte ratio, monocyte/lymphocyte ratio and c-reactive protein levels in both groups were determined using the results of venous blood samples collected during preoperative preparation and compared between the groups. RESULTS: Our study findings reveal that the monocyte/lymphocyte ratio of the group with aseptic loosening was statistically significantly different from that of the patient group who had primary total knee arthroplasty (p = 0.02). Furthermore, although c-reactive protein levels are not high enough to suggest systemic inflammation, the difference between the groups is statistically significant (p = 0.01). CONCLUSIONS: No hematological parameter that could be used in the diagnosis of aseptic loosening has been defined in the literature so far. This study demonstrated that the monocyte/lymphocyte ratio could be a helpful parameter in the diagnosis of aseptic loosening (Tab. 1, Fig. 1, Ref. 28). Text in PDF www.elis.sk © 2021
dc.identifier.doi10.4149/BLL_2021_143
dc.identifier.endpage883
dc.identifier.issn0006-9248
dc.identifier.issue12
dc.identifier.pmid34904850
dc.identifier.scopus2-s2.0-85122570901
dc.identifier.scopusqualityQ3
dc.identifier.startpage880
dc.identifier.urihttps://doi.org/10.4149/BLL_2021_143
dc.identifier.urihttps://hdl.handle.net/11480/11058
dc.identifier.volume122
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherComenius University in Bratislava
dc.relation.ispartofBratislava Medical Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241106
dc.subjectarthroplasty
dc.subjectKnee
dc.subjectmonocyte
dc.subjectneutrophil
dc.subjectrevision
dc.titleCan neutrophil-to-lymphocyte, platelet-to-lymphocyte and monocyte-to-lymphocyte ratios be useful to the diagnosis of aseptic loosening after total knee arthroplasty?
dc.typeArticle

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