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Öğe 4-h mean lactate clearance as a good predictor of adverse outcome in acute cardiogenic pulmonary edema: a pilot study(Walter De Gruyter Gmbh, 2024) Vural, Abdussamed; Karapehlivan, Mahmut; Dolanbay, Turgut; Cumaoglu, Mustafa Oguz; Hatip, Ahmet Yunus; Cetinkaya, Yakup; Unalan, AdnanObjectives This pilot study aimed to evaluate the efficacy of the 4-h mean lactate clearance (LACclr) level as a predictive factor for in-hospital outcomes, 30-day mortality, and treatment success in patients with acute cardiogenic pulmonary edema (ACPE), a significant clinical form of acute heart failure (AHF).Methods A total of 44 patients diagnosed with acute pulmonary edema were included in the study. The patients were divided into two groups based on lactate levels and negative outcomes, and lactate and LACclr levels and negative outcomes were analyzed using statistical tests such as Fisher's exact test, Student's t-test, Mann-Whitney U test, and Receiver operating characteristic (ROC) analysis.Results The results indicated a statistically significant difference in the total hospitalization length of stay according to whether the patients had a negative outcome (intubation and in-hospital mortality) (p=0.033). Additionally, the area under the curve (AUC) value for 4-h mean LACclr was 0.795 in all patients, which was statistically significant in predicting 30-day mortality (p=0.033). The optimal cut-off value for the 4-h mean LACclr in predicting 30-day mortality was found to be 5.57 %, with 80 % sensitivity and 66.7 % specificity. The threshold to rule out 30-day mortality for all patients was 18.85 with 100 % sensitivity and 30.2 % specificity (AUC, 0.795 95 % CI [0.546-1.000], p=0.033).Conclusions These findings suggest that the 4-h LACclr level, calculated within 4 h of emergency department (ED) presentation, can be used as a predictive indicator for needing intubation, in-hospital mortality, and 30-day mortality and to identify patients at higher risk for adverse outcomes.Öğe A Research on Structural Characteristics and Problems of Sheep Breeding in Nigde(KAHRAMANMARAS SUTCU IMAM UNIV, 2015) Ceyhan, Ayhan; Sekeroglu, Ahmet; Unalan, Adnan; Cinar, Mahmut; Serbester, Ugur; Akyol, Ethem; Yilmaz, ErdoganThis study was carried out to reveal the present status of sheep farms in Nigde, to detect basic priority problems and to offer some solutions to these problems. In this study, total of 96 sheep farming enterprises were chosen by stratified sampling method to represent the entire province as an example. A survey was conducted to obtain information regarding mating, lambing, milking, shearing, marketing milk and meat, grazing animals status, tools and equipment of sheep enterprises and health protection and feed utilization status. The results of analyzes showed that a large portion (68.8%) of sheep breeders were primary school graduates, while 99% of sheep farms raised only Akkaraman breed 1.0% of them raised only Merino breed, average duration of sheep breeding was 25.7 years, family labor was commonly (63.5%) used as shepherd, the average number of sheep per farm was 314.5 head and the enterprises had also 7.9 head cows, 38.1 head goats, 1.9 horses and 5.2 heads cat and dog. Besides, it was informed that 86.4% of breeders had learned sheep breeding from their ancestors, sheep farming was only source of income for 82.3% of them and was enjoyable job for 10.4% of them. It was also determined that sheep breeding was maintained in highland (40.6%), in highland and settled down (19.8%), in settled down (38.6%), and in nomadic (1.0%) system in Nigde. The 97.9% of sheep enterprises is a member of Nigde Sheep and Goat Breeders Association. Breeders expressed that high feed prices, insufficient pastures area and poor pastures quality were priority problems. They reported that needs to be done to increase in marketing price, improvement of pasture and sheep flock genetic, also increasing the forage crops cultivation area for profitable sheep breeding.Öğe Comparison of colony performances of Anatolian, Caucasian and Carniolan honeybee (Apis mellifera L.) genotypes in temperate climate conditions(PAGEPRESS PUBL, 2014) Akyol, Ethem; Unalan, Adnan; Yeninar, Halil; Ozkok, Duran; Ozturk, CahitThis study was carried out to determine the performances of Mugla and Nigde ecotypes (A. m. anatoliaca), Caucasian (A. m. caucasica) and Carniolan (A. m. carnica) honeybee genotypes in the region of central Anatolia conditions. A total of 40 colonies (each genotype group consisted of 10 colonies) were used in the study. All queens were reared at the same time and in the same apiary and were instrumentally inseminated. The average numbers of combs covered with bees were found to be 11.24 +/- 0.59, 9.51 +/- 0.42, 8.11 +/- 0.31 and 12.38 +/- 0.72 per colony respectively; the average brood areas were found to be 2825.0 +/- 240.3, 2160.6 +/- 176.8, 1701.9 +/- 129.7 and 2883.0 +/- 104.4 cm(2) per colony respectively; and the average honey yields were found to be 28.60 +/- 0.88, 15.40 +/- 0.69, 23.40 +/- 0.54 and 31.60 +/- 1.12 kg per colony in Mugla ecotype, Nigde ecotype, Caucasian and Carniolan genotypes respectively. The mean differences among the genotypes for number of combs with bees, brood area and honey yield were significant (P<0.01). These results showed that the Carniolan genotype had the best performance and Nigde ecotype had the lowest performance in temperate climate conditions. Therefore, productivity of the Nigde ecotype can be increased by a crossbreeding programme with Carniolan and Mugla genotypes.Öğe Comparison of Some Body Measurements of South Anatolian Red and Native Southern Yellow Cattle(KAHRAMANMARAS SUTCU IMAM UNIV, 2016) Unalan, AdnanThis study was conducted with the aim of determining differences between some body measurements of South Anatolian Red (SAR) and Native Southern Yellow (NSY) cows because of they were generally evaluated in the same cattle breed name in Turkey. In the present study, 92 heads of SAR cows and 100 heads of NSY cows were used as animal material. These cattle types were in in-situ conservation program of domestic animal genetic resource held in 2005. In this context, the herds for SAR and NSY cattle were established in Hatay and Adana provinces, respectively. In the study, four body measurements (Body Length: BL, Withers Height: WH, Rump Height: RH and Chest Depth: CD) of the cattle types were investigated and were compared according to these body measurements. Statistical analysis showed that the overall means (+/- SE) of BL, WH, RH and CD for SAR cows were 141.37 +/- 1.26 cm, 123.22 +/- 1.06 cm, 128.38 +/- 1.13 cm and 64.06 +/- 0.53 cm respectively. The overall means of body measurements indicated above for NSY cows were 119.29 +/- 0.84 cm, 103.29 +/- 0.68 cm, 105.70 +/- 0.79 cm and 55.63 +/- 0.39 cm respectively. Independent two-sample t-test showed that the mean differences all of body measurements between two cattle types were statistically significant (P< 0.01). The results supported that these cattle types were different cattle breeds, although they were generally evaluated in the same cattle breed name (as Native Yellow Red cattle: NYR).Öğe Determining effects of some factors on birth weight and survival rates of Holstein calves(Indian Dairy Assoc, 2017) Unalan, Adnan; Yazgan, ErtanThis study was aimed to determine the effects of calf sex, birth weight, parity, calving year and season on birth weight and survival rates of 761 Holstein calves born between 2006 and 2016 in Eastern Mediterrean Agricultural Research Institute in Adana. Analysis showed that the effects of sex and parity on birth weights of calves were statistically significant. However, the effects of calving year and season were not significant. Survival rates of calves during monthly interval were analyzed by survival analysis using life tables. According to sex cumulative survival rates (CSR) ranged from 0.871 to 0.848 and 0.970 to 0.822 for males and females respectively; according to birth weight group CSR ranged from 0.906 to 0.809 and 0.929 to 0.859 for for lower and higher birth weight groups respectively; according to season from 0.909 to 0.818, 0.927 to 0.855, 0.945 to 0.868 and 0.906 to 0.821 for winter, spring, summer and autumn respectively; and according to parity CSR ranged from 0.927 to 0.849, 0.916 to 0.813 and 0.903 to 0.835 for the first, second and third parities respectively. In conclusion, survival analysis showed that the effects of calf sex, birth weight group, calving season and parity were all not statistically significant on survival rates of Holstein calves. These results could be interpreted that survival rates of calves could be commonly affected by the other factors such as care, feeding, diseases and housing system with genetic factors.Öğe DETERMINING THE TOTAL ANTIOXIDANT STATUS AND OXIDATIVE STRESS INDEXES OF HONEY SAMPLES OBTAINED FROM DIFFERENT PHYTOGEOGRAPHICAL REGIONS IN TURKEY(PARLAR SCIENTIFIC PUBLICATIONS (P S P), 2015) Akyol, Ethem; Selamoglu, Zeliha; Dogan, Hamide; Akgul, Hasan; Unalan, AdnanThis study aimed to determine the total antioxidant and oxidant status and oxidative stress index of honey samples which were collected from 11 different phytogeographical regions in Turkey. Honey samples were kept at 4 degrees C until analysis. Total antioxidant status, total oxidant status and oxidative stress indexes were defined with in vitro analyses in extracted honey samples, and then, the obtained data were compared statistically. These characteristics of honey were analysed by the most sensitive and reliable measurement kits developed newly. In addition, biological activities of honey samples originating from different regions were also compared. As a result of the study, the highest total antioxidant capacity was observed (P<0.01) in the honey samples obtained from Duzce and Mugla regions. The results also showed that total antioxidant capacities of honey samples could change according to various phytogegraphic properties of different regions in Turkey. Besides, antioxidant properties of honey depended on phenolic compounds that could change according to plant vegetation of honey obtained from different regions.Öğe Determining the total antioxidant status and oxidative stress indexes of honey samples obtained from different phytogeographical regions in Turkey(Parlar Scientific Publications, 2015) Akyol, Ethem; Selamoglu, Zeliha; Dogan, Hamide; Akgul, Hasan; Unalan, AdnanThis study aimed to determine the total antioxidant and oxidant status and oxidative stress index of honey samples which were collected from 11 different phytogeographical regions in Turkey. Honey samples were kept at 4 °C until analysis. Total antioxidant status, total oxidant status and oxidative stress indexes were defined with in vitro analyses in extracted honey samples, and then, the obtained data were compared statistically. These characteristics of honey were analysed by the most sensitive and reliable measurement kits developed newly. In addition, biological activities of honey samples originating from different regions were also compared. As a result of the study, the highest total antioxidant capacity was observed (PO.Ol) in the honey samples obtained from Duzce and Mugla regions. The results also showed that total antioxidant capacities of honey samples could change according to various phytoge- ographic properties of different regions in Turkey. Besides, antioxidant properties of honey depended on phenolic compounds that could change according to plant vegetation of honey obtained from different regions.Öğe EFFECT OF OXALIC ACID TREATMENT IN DIFFERENT SEASONS ON VARROA (VARROA DESTRUCTOR) POPULATION IN HONEYBEE COLONIES(Parlar Scientific Publications (P S P), 2017) Akyol, Ethem; Unalan, AdnanIn honeybee colonies, insufficient struggle against diseases and parasites Or the use of wrong drugs at wrong time which reduce the productivity of colonies significantly. Additionally, these kinds of wrong applications can also threaten the human health because of chemical residues. Varroa destructor, which affects negatively the colony productivity, is the most important external parasite of the honeybees (Apis mellifera L.). Therefore, beekeepers have to use many different synthetic miticides for reducing or preventing the V. destructor damages. This study was carried out to determine the possible effects of ocalic acid treatment in different seasons on V. destructor population in honeybee colonies. Ten of total twenty honebee colonies had similar infestetion levels which were used for treatment group and ten colonies were also used as the control group. Average efficacies of oxalic acid treatment in different seasons on Varroa population in honeybee colonies in early spring (in March), summer (in June) and late autumn (in October) were found to be 80.22%, 69.72% and 84.61%, respectively (P<0.01). These results showed that oxalic acid treatment in late autumn and early spring against varroa in honeybees were about 21% and 15% more effective than summer, respectively.Öğe Estimation of Genetic Parameters and Correlations among Some Body Measurements of Holstein Calves and Effects of These Measurements on Calving Difficulty(MEDWELL ONLINE, 2009) Unalan, AdnanIn this study, some body measurements (Birth Weight: BW, Withers Height: WH, Body Length: BL and Chest Girth: CG) and Calving Difficulty Scores (CDS) of 202 calves (of which 85 were born from artificial insemination: AI, 45 were born fresh embryo transfer: ET and 62 were born Frozen Embryo Transfer: FET) obtained from Holstein heifers, which were born in the dairy herd of Cukurova Agricultural Research Institute in Adana (Turkey). In the study, it was firstly investigated the effects of producing type (AI, ET and FET) and sex of calf on all. of the body measurements and calving difficulty. Then, the effects of these body measurements on calving difficulty scores were investigated. Besides, heritabilities and genetic and phenotypic correlations among the traits were also estimated. Analysis showed that the effect of producing type was significant on all of the traits studied (p<0.01). But, the effect of sex was not statistically significant on any of them (p>0.05). Heritability estimates were 0.328, 0.287, 0.258, 0.240 and 0.152 for BW, WH, BL, CG and CDS, respectively. Genetic correlations among the body measurements: while, the highest correlation was 0.974 between CG and WH, the lowest correlation was also 0.559 between CG and BL. Genetic correlations between BW and the other measurements and CDS were 0.921, 0.879, 0.829 and 0.804 for WH, BL, CG and CDS, respectively. Genetic correlations between CDS and all of the body measurements studied were 0.804, 0.670, 0.632 and 0.495 for BW, WH, BL and CG, respectively (p<0.01). These results showed that BW was more important factor on calving difficulty than the other measurements of calves.Öğe Frequent witnessing to interparental conflict and low parental availability for leisure-time is associated with dysfunctional voiding in primary school children(Wiley, 2021) Cihan, Ahmet; Unalan, AdnanAim Aspects of parenting are an under-investigated topic amongst children with voiding complaints. We aimed to investigate the association between voiding complaints amongst children and two specific parenting-related behaviours: 1) parental availability during the child's leisure time and 2) frequency of witnessing interparental conflict. Material and Method Children aged between 6 and 11 years with their parents were the participants. Two survey forms and informed consent form were sent to potential participants via children's teacher. Voiding dysfunction complaints were evaluated with the Dysfunctional Voiding and Incontinence Symptom Scale (DVISS). Results Data analyses were performed with 1101 eligible participants. The mean duration of parental availability during the child's leisure time was below 2 hours per day. Nearly one out of every four children witnessed interparental conflict at least once a month. Age, educational level of the mother, parental availability for the child's leisure time, and frequency of witnessing parental conflicts were found to be significantly associated with DVISS ratings. Adjusting age, socioeconomic level, and educational level of the parents and later adjusting parental availability during the child's leisure time did not change the association of frequency of witnessing interparental conflict with DVISS rates. An increase in the age, educational level of the mother, and parental availability during the child's leisure time was correlated with better scores on DVISS, while an increase in the frequency of witnessing interparental conflict strongly correlated with worse scores. Conclusion Exposing children to interparental conflicts and shorter togetherness with their leisure time is associated with voiding complaints.Öğe Genetic Parameters and Correlations for Lactation Milk Yields According to Lactation Numbers in Jersey Cows(KAFKAS UNIV, VETERINER FAKULTESI DERGISI, 2010) Unalan, Adnan; Cankaya, SonerIn this study, heritabilities, genetic and phenotypic correlations for lactation milk yields were estimated using 3630 305-day lactation milk yield records obtained from cows calved from 1984 to 2007 years in Jersey cattle herd of Karakoy Agricultural State Farm in Samsun. Calving year. calving month and lactation number were assumed as fixed effect factors in statistical analysis of data. Heritabilities, genetic and phenotypic correlations were estimated by derivative-free REML with the animal model. Analysis showed that the overall means of 305-day milk yield, lactation length, dry off period and calving interval were 3467 kg, 297 days, 70 days and 367 days, respectively. Variance analysis results showed that all of the fixed effect factors were statistically significant on lactation milk yields (P<0.001). REML estimates of heritability were 0.289, 0.319, 0.324, 0.331, 0.339, 0.357 and 0.379 for lactation milk yields (from the first to seventh lactation numbers, respectively). Genetic correlations among the first and sub-sequent lactation milk yields were 0.687, 0.676, 0.631. 0.601, 0.590 and 0.551, respectively. All genetic correlations were high and statistically significant (P<0.01). High genetic correlations among lactation numbers reflected that the first lactation milk yield of cows would be useful indicator for the sub-sequent lactations and selection of breeding stock.Öğe Seasonal effects on behavioral estrus signs and estrus detection efficiency in Holstein heifers(AGRICULTURAL RESEARCH COMMUNICATION CENTRE, 2016) Unalan, AdnanIn the study, 234 Holstein heifers were observed visually during a one-year period and 1622 estrus records were used to determine seasonal effects on behavioral estrus signs and estrus detection efficiency. Estrus records were classified as standing, mounting, vaginal mucus discharging, and the other estrus signs. The rates of these estrus signs were found to be 50.6%, 22.7%, 20.7% and 6.0%. respectively and the differences were significant (P<0.01). These results showed that standing behavior was the most observable estrus sign in Holstein heifers. In addition, the rates of standing behavior in each season (66.2%, 59.7%, 50.4% and 38.0% in summer, fall, spring and winter, respectively) showed that it was also more observable sign than the other signs. The rates of estrus records according to seasons were found to be 34.4%, 32.9%, 23.6% and 9.1% in winter, fall, spring and summer, respectively and the differences were also significant (P<0.01). In the study, the mean overall estrus cycle length was found to be 21.15 +/- 1.85 days. The mean overall estrus detection efficiency was calculated as 57.8%. The mean detection efficiencies according to seasons were found to be 79.5%, 75.9%, 54.6% and 21.1% in winter, fall, spring and summer respectively. These results could be interpreted that estrus detection efficiency was decreased significantly with increase of temperature.Öğe Selection of a mathematical model to describe the lactation curves of Jersey cattle(ARCHIV FUR TIERZUCHT, 2011) Cankaya, Soner; Unalan, Adnan; Soydan, ErcanThe extent of the usefulness of a lactation model depends on how well it succeeds in imitating the biological lactation process and how well it adjust for environmental and other factors that could influence production. Therefore, the objective of this study was to compare five different lactation curve models (Wood, Cobby and Le Du, Wilmink, Exponential and Parabolic Exponential model), and to find the best model that provided a good description of the lactation curve of Jersey cattle herd. Data used in this study were the first to seventh lactation official milk yield records from monthly recording of 3 630 lactations between 1984 and 2008 in the farm. The results showed that Wood model which has minimum residual standard deviation (3.562), maximum adjusted R(2) value (91.6%) and maximum persistency value (93.3%) performed the best fit to the data and allowed a suitable description of the lactation curve. It was concluded that the Wood model provided accurate estimates of milk yield for all lactation numbers because this model was found to be more superior to the other models. Consequently, the usage of Wood model would provide some useful information on genetic improvement of the Jersey breed under pasture-based dry seasonal production systems.