No-touch isolation technique in early-stage non-small-cell lung cancer surgery: a retrospective study

Basit Öğe Kaydı
dc.contributor.authorÇetin, Mehmet
dc.contributor.authorTürk, İlteris
dc.contributor.authorGüven, Ebru Sayılır
dc.contributor.authorFındık, Göktürk
dc.contributor.authorAydoğdu, Koray
dc.contributor.authorGülhan, Selim Şakir Erkmen
dc.contributor.authorBıçakçıoğlu, Pınar
dc.date.accessioned2024-11-07T13:16:38Z
dc.date.available2024-11-07T13:16:38Z
dc.date.issued2022
dc.departmentNiğde Ömer Halisdemir Üniversitesi
dc.description.abstractBackground: In parallel with the change in circulating tumor cells, the no-touch isolation technique is offered as an option to reduce recurrences of non-small-cell lung cancer. We aimed to examine the relationship of this technique with recurrence and survival in our clinic. Materials and Methods: Among 675 patients who were operated on with the diagnosis of lung cancer between 2009 and 2015, 98 patients with tumor size of less than 3 cm in the postoperative pathology report, no visceral pleural invasion or lymph node involvement, and a negative surgical margin were included in the study. The patients were divided into two groups as patients treated with and without the no-touch isolation technique (i.e., a wedge resection group prior to lobectomy and a direct lobectomy group), and the results of recurrence and survival were evaluated statistically. Results: While adenocarcinoma was observed more frequently in the wedge resection group, squamous cell carcinoma was observed statistically more frequently among patients treated with direct lobectomy (p < 0.001). There was no statistically significant difference in recurrence or survival rates between patients treated with and without the no-touch isolation technique (p = 0.746 and p = 0.689, respectively). Conclusions: Although wedge resection before surgery is theoretically well grounded, we found that it was not clinically significant as a result of our study. The technique may prove beneficial in reevaluating chemotherapy indications based on circulating tumor cells, especially in early-stage cases where patients have not received chemotherapy, and prospective studies are needed in this regard.
dc.identifier.doi10.26663/cts.2022.023
dc.identifier.endpage146
dc.identifier.issn2548-0316
dc.identifier.issue3
dc.identifier.startpage141
dc.identifier.trdizinid1149915
dc.identifier.urihttps://doi.org/10.26663/cts.2022.023
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1149915
dc.identifier.urihttps://hdl.handle.net/11480/12477
dc.identifier.volume7
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofCurrent Thoracic Surgery
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241107
dc.subjectSolunum Sistemi
dc.subjectOnkoloji
dc.subjectBiyokimya ve Moleküler Biyoloji
dc.subjectHücre Biyolojisi
dc.subjectCerrahi
dc.subjectLung cancer
dc.subjectthoracic surgery
dc.subjectwedge resection
dc.subjectcirculated tumor cell
dc.titleNo-touch isolation technique in early-stage non-small-cell lung cancer surgery: a retrospective study
dc.typeArticle

Dosyalar

Koleksiyon

TR-Dizin İndeksli Yayınlar Koleksiyonu