Natural Compounds Used as Therapies Targeting to Amyotrophic Lateral Sclerosis

Küçük Resim Yok

Tarih

2015

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

BENTHAM SCIENCE PUBL LTD

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

Amyotrophic lateral sclerosis (ALS) is a neuromuscular disease that occurs throughout the world with no racial, ethnic or socioeconomic boundaries. Despite its high morbidity and mortality, there are limited medications available for ALS that may increase survival in patients with amyotrophic lateral sclerosis by approximately 2-3 months. Inasmuch as negative effects of riluzole on muscle atrophy and wasting, weakness, muscle spasticity, dysarthria, dysphagia, and overall patient quality of life and its different adverse effects, much attention has been paid to natural products and herbal medicines. Overall scientific reports indicate that natural products have beneficial effects on patients with ALS low side effects and multiple targets. In the present paper, we review the scientific reports on beneficial role of natural polyphenolic compounds in treatment of ALS.

Açıklama

Anahtar Kelimeler

Amyotrophic lateral sclerosis, natural substances, polyphenol, oxidative stress

Kaynak

CURRENT PHARMACEUTICAL BIOTECHNOLOGY

WoS Q Değeri

Q3

Scopus Q Değeri

Q2

Cilt

16

Sayı

3

Künye