Effect of Calcium and Phosphorus Metabolism on Static and Dynamic Pupillary Responses: Prospective Cross-Sectional Study

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Tarih

2023

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Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

Objective: To investigate the effects of serum calcium and phosphorus levels on static and dynamic pupillometry measure- ments in patients with postoperative hypoparathyroidism.Material and Methods: Pupillometry measurements were undertaken by using an automatic pupillometry to detect high photopic, low photopic, mesopic, scotopic pupil diameters with amplitude, latency, duration and veloc- ity of pupil contraction and dilatation. Duration of hypoparathyroidism and serum parathyroid hormone (PTH), calcium and phosphorus levels were recorded. Results: This study included 46 female patients with postoperative hypoparathyroidism and 61 healthy female participants. There were no significant differences between the pupil diameters at different light intensities between the study groups (p>0.05 for all). Among the dynamic pupillometric measurements, pupil contraction amplitude was significantly higher in patients with postoperative hy- poparathyroidism when compared to that of healthy controls (1.85±0.04 mm vs 1.72±0.03 mm respectively, p=0.018). There was no significant correlation between the duration of hypoparathy- roidism, serum calcium, phosphorus, and PTH levels with static and dynamic pupillometry values (p>0.05 for all), with an exception of a positive correlation between the serum calcium level and amplitude of contraction (r=0.322, p=0.029). Conclusion: Pupil diameters at different light intensities were not affected in patients with postoper- ative hypoparathyroidism, but pupil contraction amplitude was higher than in healthy individuals.

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Anahtar Kelimeler

Endokrinoloji ve Metabolizma, Klinik Nöroloji, Nörolojik Bilimler, Odyoloji ve Konuşma-Dil Patolojisi, Phosphorus, Calcium, hypoparathyroidism, parathyroid hormone, pupil disorders

Kaynak

Türkiye Klinikleri Oftalmoloji Dergisi

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Scopus Q Değeri

Cilt

32

Sayı

2

Künye