The impact of the apelinergic system in coronary collateral formation

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dc.contributor.authorOzsoyler, Ibrahim
dc.contributor.authorUcak, Haci Ali
dc.contributor.authorBadak, Tolga Onur
dc.contributor.authorCakallioglu, Ahmet
dc.contributor.authorBayraktar, Muhammet
dc.contributor.authorArslan, Ahmet Suha
dc.date.accessioned2024-11-07T13:32:26Z
dc.date.available2024-11-07T13:32:26Z
dc.date.issued2023
dc.departmentNiğde Ömer Halisdemir Üniversitesi
dc.description.abstractBackground: This study aims to examine the relationship between the development of coronary collateral circulation and serum elabela levels. Methods: Between January 2020 and December 2021, a total of 50 control individuals (29 males, 21 females; mean age: 63.2 +/- 10.0 years; range, 52 to 73 years) with no significant coronary artery disease as confirmed by angiography (Group 1) and 100 patients (55 males, 45 females; mean age: 66.6 +/- 9.6 years; range, 56 to 75 years) with coronary artery disease were included. The patients were further divided into two equal groups according to the Rentrop classification as poor (Group 2) and good coronary collateral circulation (Group 3). All groups were compared in terms of several parameters, particularly serum elabela levels. Results: Serum elabela levels were found to be statistically higher in the group with good collateral than the other groups (p<0.05). Low serum elabela levels increased the risk of developing weak collaterals by 2.43 times. Conclusion: The elabela protein is directly related to good collateral development and can be considered a potential agent for treatment.
dc.identifier.doi10.5606/tgkdc.dergisi.2023.24422
dc.identifier.endpage198
dc.identifier.issn1301-5680
dc.identifier.issue2
dc.identifier.pmid37484641
dc.identifier.scopus2-s2.0-85158970063
dc.identifier.scopusqualityQ3
dc.identifier.startpage192
dc.identifier.trdizinid1176991
dc.identifier.urihttps://doi.org/10.5606/tgkdc.dergisi.2023.24422
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1176991
dc.identifier.urihttps://hdl.handle.net/11480/15415
dc.identifier.volume31
dc.identifier.wosWOS:000983239400008
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherBaycinar Medical Publ-Baycinar Tibbi Yayincilik
dc.relation.ispartofTurk Gogus Kalp Damar Cerrahisi Dergisi-Turkish Journal of Thoracic and Cardiovascular Surgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241106
dc.subjectApelinergic system
dc.subjectcoronary artery disease
dc.subjectcoronary collateral
dc.subjectelabela
dc.titleThe impact of the apelinergic system in coronary collateral formation
dc.title.alternativeApelinerjik sistemin koroner kollateral oluşumuna etkisi
dc.typeArticle

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