Vortex-assisted sequential liquid-phase micro-extraction of E127 and E129 in foodstuffs and pharmaceuticals

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dc.authoridBisgin, Abdullah Taner/0000-0002-3557-3090
dc.contributor.authorBisgin, Abdullah Taner
dc.date.accessioned2024-11-07T13:24:36Z
dc.date.available2024-11-07T13:24:36Z
dc.date.issued2023
dc.departmentNiğde Ömer Halisdemir Üniversitesi
dc.description.abstractIn the present study, sequential liquid-phase micro-extraction (LPME) method based on amphiphile (1-pentanol) and ion-pair agent as the green chemicals for micro-separation, preconcentration and UV-vis micro-spectrophotometric determination of Erythrosine (E127) and Allura red (E129) in foodstuffs and pharmaceuti-cals was developed for the first time. 1-pentanol was used as extraction solvent for micro-extraction of E127 and to prepare alkanol based ion-pair solvent with tetra-pentyl ammonium bromide for micro-extraction of E129. E127 and E129 were determined by spectrophotometer at 538 and 506 nm, respectively. Micro-separation and micro-extraction parameters of the methods including pH, type and volume of 1-pentanol and ion-pair solvent, time of vortex and centrifugation were examined in detail and optimized. At the optimum conditions, inter-ference effects of matrix components and effect of sample volume on the micro-extraction methods were investigated. Limit of detection and limit of quantification were found as 3.2 mu g/L, 8.4 mu g/L for E127 and 5.2 mu g/ L, 13.7 mu g/L for E129, respectively. 15 preconcentration factor was attained for each of the dyes. The possible extraction mechanisms of the alkanol based micro-extraction for E127 and ion-pair agent based micro-extraction for E129 were elucidated in detail and also showed with images. Finally, the proposed sequential micro -separation technique was validated by analyte addition and recovery studies and applied to determine E127 and E129 contents of commercially available foodstuffs and pharmaceuticals in Turkish markets and pharmacies.
dc.identifier.doi10.1016/j.microc.2023.108420
dc.identifier.issn0026-265X
dc.identifier.issn1095-9149
dc.identifier.scopus2-s2.0-85146466280
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1016/j.microc.2023.108420
dc.identifier.urihttps://hdl.handle.net/11480/14208
dc.identifier.volume187
dc.identifier.wosWOS:000971993700001
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherElsevier
dc.relation.ispartofMicrochemical Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241106
dc.subjectAllura red
dc.subjectErythrosine
dc.subjectE127
dc.subjectE129
dc.subjectIon-pair agent
dc.subjectLiquid-phase micro-extraction
dc.subject1-pentanol
dc.subjectUV-visible spectrophotometry
dc.titleVortex-assisted sequential liquid-phase micro-extraction of E127 and E129 in foodstuffs and pharmaceuticals
dc.typeArticle

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