Investigation of the Frequency of Cryptosporidium spp. and Giardia intestinalis in Patients with Suppressed Immune System

Basit Öğe Kaydı
dc.contributor.authorBayraktar, Mehmet
dc.contributor.authorCömert, Medine
dc.contributor.authorÖztürk, Ali
dc.date.accessioned2024-11-07T13:19:00Z
dc.date.available2024-11-07T13:19:00Z
dc.date.issued2022
dc.departmentNiğde Ömer Halisdemir Üniversitesi
dc.description.abstractObjective: Giardia intestinalis and Cryptosporidium spp. are important agents causing diarrhea in developing and developed countries. If untreated, these agents may cause severe life-threatening diarrhea, especially in immunocompromised people and children. This study aimed to investigate the frequency of Cryptosporidium spp. and G. intestinalis in the stool samples of immunocompromised patients who applied to Harran University Research and Application Hospital. Methods: This study was carried out with a total of 100 patients with immunosuppression and diarrhea who were admitted to our hospital between January 2017 and January 2019. Cryptosporidium spp. and G. intestinalis antigens were investigated in stool samples of the patients by immunochromatographic (IC) method and oocyst, and cyst-trophozoite were examined with Native-Lugol and Kinyoun acid-fast staining. Results: G. intestinalis was detected in eight (8%) patients. Seven of them (14%) were pediatric patients (n=50) and one (2%) was an adult female patient (n=50). Cryptosporidium spp. was detected in 3 (3%) patients. Of these, two (4%) were children patients and one (2%) was an adult female patient. Our results also demonstrated that both Cryptosporidium and Giardia were more found in immunocompromised patients, especially in pediatric ones (4% and 14% respectively). Conclusion: Although the cost of the IC method, which detects antigens in stool samples is high, it is easy to work with, provides early results and it also helps to overcome the difficulties in active diagnostic methods. Despite the limited number of investigated samples, our findings showed that the incidence of infections from these two parasites is higher than in other studies conducted in Turkey or European countries.
dc.identifier.doi10.30934/kusbed.1156716
dc.identifier.endpage228
dc.identifier.issn2149-8571
dc.identifier.issue3
dc.identifier.startpage225
dc.identifier.trdizinid1128655
dc.identifier.urihttps://doi.org/10.30934/kusbed.1156716
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1128655
dc.identifier.urihttps://hdl.handle.net/11480/12800
dc.identifier.volume8
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofKocaeli Üniversitesi Sağlık Bilimleri Dergisi
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241107
dc.subjectTıbbi Araştırmalar Deneysel
dc.subjectHalk ve Çevre Sağlığı
dc.subjectMikrobiyoloji
dc.subjectParazitoloji
dc.subjectPediatri
dc.subjectTıbbi Laboratuar Teknolojisi
dc.subjectGiardia intestinalis
dc.subjectdiarrhea
dc.subjectCryptosporidium spp
dc.subjectchromatographic method
dc.subjectimmunosuppressed
dc.titleInvestigation of the Frequency of Cryptosporidium spp. and Giardia intestinalis in Patients with Suppressed Immune System
dc.typeArticle

Dosyalar

Koleksiyon

TR-Dizin İndeksli Yayınlar Koleksiyonu