Niğde yöresinde tropikal Theileriosis'in aşılama sonrası epidemiyolojisi
Küçük Resim Yok
Tarih
2001
Yazarlar
Dergi Başlığı
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Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Bu çalışma, Mart 1998-Nisan 1999 tarihleri arasında Niğde ili Çukurkuyu kalabasında aşılama sonrası tropikal theileriosis'in epidemiyolojisinin araştırılması amacı ile yapılmıştır. Çalışma başlangıcında Theileria annulata yönünden hem İFA testi ile serolojik hem de kan frotilerinde eritrositer form (piroplasm) bakımından negatif olduğu tespit edilen 69 sığır çalışma grubu olarak belirlenmiş ve bunlardan 46'sı attenüe 107 hücrelik bir dozda T. annulata şizont aşısı ile aşılanmış, 23'ü kontrol olarak bırakılmıştır. Aşılamadan sonra bir yıl süreyle her ay çalışma merkezine gidilerek materyal alınmıştır. Theileria annulata'nm aşılama öncesi mikroskobik ve serolojik prevalansı %0 bulunmuş, aşılamadan 30 gün sonra yapılan incelemelerde serokonversiyon oranı %SO,4 olarak saptanmıştır, Hastalık mevsimi boyunca aşılanan sığırların 2 (%4,3)'si piroplasm taşıyıcısı (portör) olarak belirlenmiştir. Kontrol grubu olarak bırakılan sığırlardan sadece 4 (%17,3)'ü T. annulata'yz karşı seropozitif, 2 (%8,6)'si ise piroplasm taşıyıcısı olarak tespit edilmiştir, Bu çalışma süresince hayvanların hiçbirinde klinik T. annulata enfeksiyonu görülmemiştir. Aşılamadan sonra seropozitiflik 2 yaş üstü grupta 6'ncı aydan itibaren azalarak 12 ay devam ettiği halde, 2 yaş altı grupta 4'üncü ayda düşmeye başlamış ve 6'ncı ayda ise tamamen sıfırlanmıştır. T. annulata piroplasm antijenine karşı antikor titresi 1:20 ve 1:2560, şizont antijenine karşı antikor litresi 1:40 ve 1:640 arasında saptanmıştır. En yüksek piroplasm antijenine karşı antikor titresi Ağustos ve Eylül aylarında, şizont antijenine karşı antikor titresi ise Haziran ayında görülmüştür. Araştırma süresince hayvanlar üzerinde Hyalomma soyuna bağlı 2 adet Hyalomma anatolicum excavatum ve l adet Hyalomma a, anatolicum kenesi bulunmuştur.
This study was carried out on the post-vaccination epidemiology of tropical theileriosis in Çukurkuyu town of Niğde between March 1998 and April 1999. At the beginning of the study, 69 cattle were removed from herds in the study site and examined for Theileria annulata infection using the İFA test and microscopical examination, Ali the cattle were found to be free from the infection and were vaccinated with 107 attenuated T. annulata schizont vaccine cells. Twenty-three cattle were allocated as non-vaccinated controls. After the vaccination, the study site was visited önce a month for a period of one year. The results showed that both the pre-vaccination microscopic prevalence and pre-vaccination seroprevalance of T. annulata were 0%. in the vaccinated cattle, the seroconversion rate was 80,4% on the 30th day after-vaccination. Two of the vaccinated cattle (4.3%) became piroplasm carriers during the tropical theileriosis season. Only 4 (17.3%) animals out of the non-vaccinated control cattle became seropositive to T. annulata and 2 animals (8,6%) became piroplasm carriers during the endemic season. None the animals in the study sample or the other animals in the study sites developed clinical tropical theileriosis during the period of this study. Seropositivity continued for 12 months in the vaccinated cattle more than 2 years old. On the other hand, seropositivity continued 6 months in the vaccinated cattle less than 2 years old. in sera, the titres of antibodies against piroplasm and schizont antigens of T. annulata varied between 1:20 to 1:2560 and 1:40 to 1:640 respectively. The highest level of antibody titre against piroplasm antigen occurred in August and September and against the schizont antigen only in June. Throughout the study, only 2 Hyalomma anatolicum excavatum and l Hyalomma anatolicum anatolicum were found on cattle.
This study was carried out on the post-vaccination epidemiology of tropical theileriosis in Çukurkuyu town of Niğde between March 1998 and April 1999. At the beginning of the study, 69 cattle were removed from herds in the study site and examined for Theileria annulata infection using the İFA test and microscopical examination, Ali the cattle were found to be free from the infection and were vaccinated with 107 attenuated T. annulata schizont vaccine cells. Twenty-three cattle were allocated as non-vaccinated controls. After the vaccination, the study site was visited önce a month for a period of one year. The results showed that both the pre-vaccination microscopic prevalence and pre-vaccination seroprevalance of T. annulata were 0%. in the vaccinated cattle, the seroconversion rate was 80,4% on the 30th day after-vaccination. Two of the vaccinated cattle (4.3%) became piroplasm carriers during the tropical theileriosis season. Only 4 (17.3%) animals out of the non-vaccinated control cattle became seropositive to T. annulata and 2 animals (8,6%) became piroplasm carriers during the endemic season. None the animals in the study sample or the other animals in the study sites developed clinical tropical theileriosis during the period of this study. Seropositivity continued for 12 months in the vaccinated cattle more than 2 years old. On the other hand, seropositivity continued 6 months in the vaccinated cattle less than 2 years old. in sera, the titres of antibodies against piroplasm and schizont antigens of T. annulata varied between 1:20 to 1:2560 and 1:40 to 1:640 respectively. The highest level of antibody titre against piroplasm antigen occurred in August and September and against the schizont antigen only in June. Throughout the study, only 2 Hyalomma anatolicum excavatum and l Hyalomma anatolicum anatolicum were found on cattle.
Açıklama
Anahtar Kelimeler
Parazitoloji, Genel ve Dahili Tıp
Kaynak
Türkiye Parazitoloji Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
25
Sayı
3
