Investigation of a Probiotic Yeast as a Cholesterol Lowering Agent on Rats Fed on a High Cholesterol Enriched Diet

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dc.authorid0000-0001-9755-5448
dc.contributor.authorAloglu, Hatice Sanlidere
dc.contributor.authorOzer, Ezgi Demir
dc.contributor.authorOner, Zubeyde
dc.contributor.authorSavas, Hasan Basri
dc.contributor.authorUz, Efkan
dc.date.accessioned2019-08-01T13:38:39Z
dc.date.available2019-08-01T13:38:39Z
dc.date.issued2015
dc.departmentNiğde ÖHÜ
dc.description.abstractProbiotic yeast, Cryptococcus humicola M5-2 strain, which has high cholesterol assimilation feature and isolated from traditionally produced cheese, was investigated in vivo. This study was conducted to determine cholesterol assimilation ability of C. humicola M5-2 in vivo and specify the effect of the strain on serum total cholesterol, HDL/LDL cholesterol and triglycerides levels in rats fed on cholesterol-enriched diet. C. humicola had the ability to assimilate cholesterol at the rate of 73.33% in media. The strain was used with two different concentrations in animal feed (high and low doses containing 2% and 0.1% lyophilized strains, respectively). When the treatment groups were compared, low dose feeding group had the positive results in terms of testing values. According to the results of serum analysis, triglyceride and total cholesterol level were decreased by 25% and 1.34% respectively. Especially, decreasing the percentage rate of triglyceride has not obtained in other in vivo studies. It is thought that health promoting effect will be possible when the obtained isolate is consumed with fermented foods.
dc.description.sponsorshipTUBITAK (The Scientific and Technical Research Council of Turkey) [111 S 513]; TUBITAK-SBAG group
dc.description.sponsorshipThis study was supported as a project (111 S 513) by TUBITAK (The Scientific and Technical Research Council of Turkey). We would like to thank to TUBITAK-SBAG group for supporting to the project. We also thank to Research Assistant Cem Okan Ozer for all assistance.
dc.identifier.doi10.9775/kvfd.2015.13143
dc.identifier.endpage689
dc.identifier.issn1300-6045
dc.identifier.issue5
dc.identifier.scopus2-s2.0-84934753273
dc.identifier.scopusqualityQ3
dc.identifier.startpage685
dc.identifier.trdizinid174704
dc.identifier.urihttps://dx.doi.org/10.9775/kvfd.2015.13143
dc.identifier.urihttps://hdl.handle.net/11480/3879
dc.identifier.volume21
dc.identifier.wosWOS:000362666900010
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.institutionauthor[0-Belirlenecek]
dc.language.isoen
dc.publisherKAFKAS UNIV, VETERINER FAKULTESI DERGISI
dc.relation.ispartofKAFKAS UNIVERSITESI VETERINER FAKULTESI DERGISI
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCryptococcus humicola
dc.subjectCholesterol
dc.subjectProbiotics
dc.subjectAnimal experiment
dc.titleInvestigation of a Probiotic Yeast as a Cholesterol Lowering Agent on Rats Fed on a High Cholesterol Enriched Diet
dc.typeArticle

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