Transportation of Poorly Soluble Drug Molecules from the Organic Phase to the Aqueous Phase by Using Phosphorylated Calixarenes

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dc.authorid0000-0003-2904-160X
dc.contributor.authorBayrakci, Mevlut
dc.contributor.authorErtul, Seref
dc.contributor.authorYilmaz, Mustafa
dc.date.accessioned2019-08-01T13:38:39Z
dc.date.available2019-08-01T13:38:39Z
dc.date.issued2011
dc.departmentNiğde ÖHÜ
dc.description.abstractThis study is the first report on the extraction of poorly soluble drug molecules such as nifedipine, niclosamide, and furosemide from the organic phase to the aqueous phase by water-soluble p-phosphonate calix[n]arene receptors via a liquid-liquid phase extraction process. These water-soluble calixarene derivatives were easily obtained from the reaction between their corresponding chloromethylated derivatives and trimethyl phosphite. From the liquid-liquid phase extraction studies, it was observed that the size of the p-phosphonate calix[n]arenes changed the extraction percentage of selected drug molecules.
dc.description.sponsorshipS.U. Research Foundation [BAP: 10101016]
dc.description.sponsorshipThe authors gratefully would like to thank S.U. Research Foundation (BAP: 10101016) for financial support.
dc.identifier.doi10.1021/je2004319
dc.identifier.endpage4479
dc.identifier.issn0021-9568
dc.identifier.issue12
dc.identifier.scopus2-s2.0-83455218258
dc.identifier.scopusqualityQ2
dc.identifier.startpage4473
dc.identifier.urihttps://dx.doi.org/10.1021/je2004319
dc.identifier.urihttps://hdl.handle.net/11480/4669
dc.identifier.volume56
dc.identifier.wosWOS:000297608800030
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthor[0-Belirlenecek]
dc.language.isoen
dc.publisherAMER CHEMICAL SOC
dc.relation.ispartofJOURNAL OF CHEMICAL AND ENGINEERING DATA
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.titleTransportation of Poorly Soluble Drug Molecules from the Organic Phase to the Aqueous Phase by Using Phosphorylated Calixarenes
dc.typeArticle

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