A Study of Vitamin D and Calcium Level in Beta Thalassemia Major in Duhok Province

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dc.contributor.authorAli, Ghorbat
dc.contributor.authorNajeeb, Malika
dc.contributor.authorJubrail, Amad
dc.contributor.authorSelamoğlu, Zeliha
dc.date.accessioned2024-11-07T13:16:25Z
dc.date.available2024-11-07T13:16:25Z
dc.date.issued2019
dc.departmentNiğde Ömer Halisdemir Üniversitesi
dc.description.abstract?-thalassemia major is severe hemolytic anemia which requires repeated blood transfusion and forsurvival, which leading to iron overload. Serious complications due to iron over load are recognizedin the thalassemia patients. objectives Vitamin D and calcium are important factors for homeostasisof calcium in this study. This study was conducted for a period of two year including from patientswith ?- thalassemia major from Duhok Thalassemia Centre between 2014 -2015. Thirty eighth ?thalassemia major patients and thirty eighth persons with age- matched as control group wereenrolled in the study. Serum concentration of 25- hydroxy vitamin D and calcium were estimated byenzyme linked fluorescent assay and colorimetric method, respectively. In patients, the level ofserum 25- hydroxy vitamin D was significantly lower 11.11±4.36 ng/mL compared with controlgroup (14.03±5.96ng/mL). Vitamin D deficiency is observed about 94.73% in patients. The meanlevel of serum calcium in patients group is 7.9±0.47mg/dL and 8.98±0.77 mg/dL in control group.There was a statistically significant difference in serum calcium value between patients and controlgroup. 44.73% of patients have hypocalcaemia. This study demonstrated a high prevalence ofVitamin D deficiency and low total serum calcium levels in thalassemia patients with a significantlylower than healthy group. Hypocalcemia and vitamin D deficiency may be results from the negativeeffect of the repeated blood transfusion and malnourishment.
dc.identifier.doi10.24925/turjaf.v7i11.1924-1927.2893
dc.identifier.endpage1927
dc.identifier.issn2148-127X
dc.identifier.issue11
dc.identifier.startpage1924
dc.identifier.trdizinid355369
dc.identifier.urihttps://doi.org/10.24925/turjaf.v7i11.1924-1927.2893
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/355369
dc.identifier.urihttps://hdl.handle.net/11480/12294
dc.identifier.volume7
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofTürk Tarım - Gıda Bilim ve Teknoloji dergisi
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241107
dc.subjectGenel ve Dahili Tıp
dc.subjectHematoloji
dc.subjectOnkoloji
dc.titleA Study of Vitamin D and Calcium Level in Beta Thalassemia Major in Duhok Province
dc.typeArticle

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