Does central venous lactate measurement replace arterial lactate measurement in cardiac surgery?

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dc.contributor.authorTezcan, Büşra
dc.contributor.authorMungan, İbrahim
dc.contributor.authorŞaylan, Alev
dc.contributor.authorAdemoğlu, Derya
dc.contributor.authorSarı, Sema
dc.contributor.authorBayındır Dicle, Çilem
dc.contributor.authorAytekin, Bahadır
dc.date.accessioned2024-11-07T10:39:48Z
dc.date.available2024-11-07T10:39:48Z
dc.date.issued2021
dc.departmentNiğde Ömer Halisdemir Üniversitesi
dc.description.abstractObjective: Lactate levels, which provide valuable information about the adequacy of tissue perfusion, are usually measured by blood gas analyzers simultaneously with blood gases. Although arterial blood is the “gold standard” for measurement of lactate, the interchangeable use of arterial and venous lactate measurements can avoid increased costs and iatrogenic anemia resulting from frequent blood sampling when evaluation of venous blood gas samples are preferred. In this study; we aimed to examine the correlation and agreement between the arterial lactate (AL) and central venous lactate (CVL) values in patients undergoing on-pump cardiac surgery. Method: Adult patients who had both arterial and central venous blood gas sampling simultaneously in three stages (T1: after anesthesia induction, T2: during cross- clamping, T3: during skin closure) of operation as part of anesthetic management were eligible for inclusion in this retrospective study. CVL and AL concentrations were estimated during blood gas analysis at stages T1, T2 and T3. Spearman Rho and Bland-Altman Tests were used to assess correlation and agreement between AL and CVL measurements, respectively. Results: Totally 366 pairs of blood samples were obtained from 122 eligible patients. The 95% limits of agreement were -0.07 to -0.00 at T1; 0.30 to -0.10 at T2 and -0.16 to -0.03 at T3. The 95% Cls were detected 0.86 to 0.93 (r=0.90 and p<0.0001) at T1;0.95 to 0.97 at T2 (r=0.96 and p<0.0001) and 0.92 to 0.96 (r=0.94 and p<0.0001) at T3. Conclusion: Although sampling from arterial lactate can be considered as the “gold standard” for lactate measurement, sampling from central venous blood is an acceptable alternative for lactate measurement in on-pump cardiac surgery patients. © Copyright Anesthesiology and Reanimation Specialists’ Society. This journal published by Logos Medical Publishing. Licenced by Creative Commons Attribution 4.0 International (CC)
dc.identifier.doi10.5222/jarss.2020.80299
dc.identifier.endpage266
dc.identifier.issn1300-0578
dc.identifier.issue1
dc.identifier.scopus2-s2.0-85141898926
dc.identifier.scopusqualityQ4
dc.identifier.startpage261
dc.identifier.trdizinid424908
dc.identifier.urihttps://doi.org/10.5222/jarss.2020.80299
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/424908
dc.identifier.urihttps://hdl.handle.net/11480/11219
dc.identifier.volume29
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherAnestezi Dergisi
dc.relation.ispartofAnestezi Dergisi
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241106
dc.subjectAgreement
dc.subjectArterial lactate
dc.subjectCardiac surgery
dc.subjectCorrelation
dc.subjectVenous lactate
dc.titleDoes central venous lactate measurement replace arterial lactate measurement in cardiac surgery?
dc.title.alternativeKardiyak cerrahide santral venöz laktat ölçümü arteryel laktat ölçümünün yerini tutabilir mi?
dc.typeReview Article

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