Seroprevalence of hepatitis E virus infection in acute leukemia patients with allogeneic transplantation

Basit Öğe Kaydı
dc.contributor.authorİbrahim, Bashar
dc.contributor.authorHeydarlou, Mehdi Meskini
dc.contributor.authorÖztürk, Ali
dc.date.accessioned2024-11-07T13:19:28Z
dc.date.available2024-11-07T13:19:28Z
dc.date.issued2020
dc.departmentNiğde Ömer Halisdemir Üniversitesi
dc.description.abstractAim: Hepatitis E Virus (HEV) infection is an emerging threat in allogeneic Hematopoietic Stem Cell Transplant (allo-HSCT) recipients. The aim of this study was to determine the prevalence of HEV infection in patients with acute leukemia before and after the transplantation.Material and Methods: The study was carried out with the serum samples taken before and after the transplantation from patients (n=42) with acute leukemia, who were 4 months to 64 years of age and who had allogenic transplant at Gazi University Hospital. All samples were tested in terms of HEV-specific anti-IgG and IgM positive value by using ELISA kit.Results: While 1 (2.3%) of the samples that were included in the study was positive anti-HEV IgG before transplantation, it was found negative after the transplantation (58th month). Positive anti-HEV IgM was not found before and after the transplantation in the collected samples. The average age of the seronegative group was determined as 30.8 ± 33.1 for male and female, respectively. There was no statistically significant difference in terms of anti-HEV IgM positivity and anti-HEV IgG positivity compared with seronegative cases of seropositive cases.Conclusions: This study was conducted to determine the prevalence of HEV infection in allogeneic stem cell patients. With this study, the incidence and importance of HEV can be determined in these patients before and after transplantation. This study can also create an important epidemiological data for our country.
dc.identifier.doi10.5455/annalsmedres.2020.07.720
dc.identifier.endpage2271
dc.identifier.issn2636-7688
dc.identifier.issue9
dc.identifier.startpage2268
dc.identifier.trdizinid409563
dc.identifier.urihttps://doi.org/10.5455/annalsmedres.2020.07.720
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/409563
dc.identifier.urihttps://hdl.handle.net/11480/13149
dc.identifier.volume27
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofAnnals of Medical Research
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241107
dc.subjectGenel ve Dahili Tıp
dc.subjectMikrobiyoloji
dc.subjectİmmünoloji
dc.titleSeroprevalence of hepatitis E virus infection in acute leukemia patients with allogeneic transplantation
dc.typeArticle

Dosyalar

Koleksiyon

TR-Dizin İndeksli Yayınlar Koleksiyonu