MAY SINGLE ONE LEVEL INTRADISCAL AUTOLOGOUS PLATELET RICH PLASMA INJECTION PLAY A ROLE IN THE TREATMENT OF DISCOGENIC PAIN? RESULTS AT SIX MONTH FOLLOW-UP

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dc.contributor.authorSevgili, Ubeydullah
dc.contributor.authorSarı, Ahmet Sinan
dc.date.accessioned2024-11-07T13:16:29Z
dc.date.available2024-11-07T13:16:29Z
dc.date.issued2020
dc.departmentNiğde Ömer Halisdemir Üniversitesi
dc.description.abstractObjective: Low back pain is spreading both in older and younger people in a fast manner. Discogenic pain resulting from degeneration of the intervertebral disc is responsible for 40% or more of the cases of low back pain. We hypothesized that single one level intradiscal autologous platelet rich plasma (PRP) injection might provide remarkable pain relief and return to pre-illness activity level in the patients suffering from discogenic pain. Material and Methods: Twenty-two patients underwent injections of just one 3ml dose of PRP into one intervertebral disc space (single one level intradiscal autologous PRP injection) for discogenic pain. The patients were evaluated by visual analogue score (VAS) and Oswestry Disability Index (ODI) score before intradiscal PRP treatment and at six months after intradiscal PRP treatment. Results: The average pre-treatment VAS and ODI scores were 5.6±1.0 and 55.0% ± 11.6% respectively. The average VAS and ODI scores at six months after intradiscal PRP treatment were 1.3±1.0 and 23.2% ± 11.2% respectively and the differences were statistically significant (p<0.01). Conclusion: The present study demonstrates that single one level intradiscal PRP injection may provide remarkable pain relief and may increase the return to pre-illness activity level in the patients suffering from discogenic pain. For evaluation of the efficacy of this treatment, randomized placebo-controlled trials are needed.
dc.identifier.doi10.24938/kutfd.626463
dc.identifier.endpage49
dc.identifier.issn2148-9645
dc.identifier.issue1
dc.identifier.startpage39
dc.identifier.trdizinid377784
dc.identifier.urihttps://doi.org/10.24938/kutfd.626463
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/377784
dc.identifier.urihttps://hdl.handle.net/11480/12357
dc.identifier.volume22
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofKırıkkale Üniversitesi Tıp Fakültesi Dergisi
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241107
dc.subjectTıbbi Araştırmalar Deneysel
dc.subjectGenel ve Dahili Tıp
dc.subjectRomatoloji
dc.subjectKalp ve Kalp Damar Sistemi
dc.titleMAY SINGLE ONE LEVEL INTRADISCAL AUTOLOGOUS PLATELET RICH PLASMA INJECTION PLAY A ROLE IN THE TREATMENT OF DISCOGENIC PAIN? RESULTS AT SIX MONTH FOLLOW-UP
dc.typeArticle

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