The sensitivity of the human chromosomes to ethyl methane sulfonate (EMS) [Etil metansulfonat (EMS)'ye i·nsan kromozomlari{dotless}ni{dotless}n hassasiyeti]
Küçük Resim Yok
Tarih
2010
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
The aim of this study was to determine the chromosomal susceptibility to breakages by the mutagen Ethyl methanesulfonate (EMS). For this reason, human peripheral blood lymphocytes were treated with varying concentrations of EMS (5×10-4M, 10-3M and 2×10-3M) for 24 and 48 hours. The percentages of chromosomal fragmentations in EMS-treated and untreated (control) cells were found to be statistically significant. In addition, the extent of breakages of the same chromosomes correlated with the concentrations of the chemical. The chromosomes that were fragmented most as a result of EMS-treatment in descending order were 1, 2, 6, 4, X, 7, 3, 5, 9, and 8.
Açıklama
Anahtar Kelimeler
Chromosome damage, Ethyl methanesulfonate (EMS), Human lymphocytes, Lymphocyte culture
Kaynak
Journal of Cell and Molecular Biology
WoS Q Değeri
Scopus Q Değeri
Cilt
45511
Sayı
45293
