The sensitivity of the human chromosomes to ethyl methane sulfonate (EMS) [Etil metansulfonat (EMS)'ye i·nsan kromozomlari{dotless}ni{dotless}n hassasiyeti]

dc.contributor.authorBudak Diler S.
dc.contributor.authorTopaktaş M.
dc.date.accessioned2019-08-01T13:38:39Z
dc.date.available2019-08-01T13:38:39Z
dc.date.issued2010
dc.departmentNiğde ÖHÜ
dc.description.abstractThe aim of this study was to determine the chromosomal susceptibility to breakages by the mutagen Ethyl methanesulfonate (EMS). For this reason, human peripheral blood lymphocytes were treated with varying concentrations of EMS (5×10-4M, 10-3M and 2×10-3M) for 24 and 48 hours. The percentages of chromosomal fragmentations in EMS-treated and untreated (control) cells were found to be statistically significant. In addition, the extent of breakages of the same chromosomes correlated with the concentrations of the chemical. The chromosomes that were fragmented most as a result of EMS-treatment in descending order were 1, 2, 6, 4, X, 7, 3, 5, 9, and 8.
dc.identifier.endpage34
dc.identifier.issn1303-3546
dc.identifier.issue45293
dc.identifier.startpage25
dc.identifier.urihttps://hdl.handle.net/11480/1018
dc.identifier.volume45511
dc.institutionauthor[0-Belirlenecek]
dc.language.isotr
dc.relation.ispartofJournal of Cell and Molecular Biology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectChromosome damage
dc.subjectEthyl methanesulfonate (EMS)
dc.subjectHuman lymphocytes
dc.subjectLymphocyte culture
dc.titleThe sensitivity of the human chromosomes to ethyl methane sulfonate (EMS) [Etil metansulfonat (EMS)'ye i·nsan kromozomlari{dotless}ni{dotless}n hassasiyeti]
dc.typeArticle

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