QUORUM SENSING INHIBITION AND ANTIMICROBIAL EFFECT OF SUMAC (RHUS CORIARIA L.) PHENOLIC EXTRACT ON THE GROWTH OF PATHOGENIC BACTERIA
Küçük Resim Yok
Tarih
2019
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Parlar Scientific Publications (P S P)
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Plant secondary metabolites are phenolic compounds which have many bioactivities such as antioxidant, antimicrobial and also inhibition of quorum sensing-regulated violacein pigment production properties. The objective of this study was to determine the antioxidant, antimicrobial activity and quorum sensing inhibition (QSI) activity by the three phenolic extract (water, ethanol and acetone) of the fruits of three different wildly grown sumac (Rhus coriaria L.) genotypes from Diyarbakir region of Turkey. The phenolic content of extract was determined as within range 152,07 +/- 7,5- 452,4 +/- 17,6 mu g GAE g dw(-1). The antioxidant activity determined through the ABTS(+) method was ranged from 17,89 +/- 0,92 to 41,75 +/- 1,11 mu mol TE/g dw. The all of the tested phenolic extracts were able to inhibit all the evaluated bacteria by the disc diffusion assay in the range of 6.29 +/- 0.71-27.84 +/- 1.42 mm and inhibited the quorum sensing phenomena in bacteria within ranges from 16.27 +/- 0.59 to 24.78 +/- 0.68 mm, among them, for the activity, the ethanoic extraction was the most effective solvent system for Rhus coriaria phenolic bioactivity. The sumac phenolic extract exhibited high antioxidant capacity, antimicrobial and anti-quorum sensing properties. To our knowledge, this is the first report on the QSI activity of sumac fruit extract. The discovery of nontoxic novel compounds within antibacterial and QSI activity could lead to the development of antimicrobial therapeutic agents that can be alternative and complementary treatments against antibiotic resistant pathogenic bacteria.
Açıklama
Anahtar Kelimeler
Rhus coriaria L., phenolic extracts, antioxidant activity, quorum sensing inhibition, antimicrobial activity
Kaynak
Fresenius Environmental Bulletin
WoS Q Değeri
Q4
Scopus Q Değeri
Cilt
28
Sayı
11
