QUORUM SENSING INHIBITION AND ANTIMICROBIAL EFFECT OF SUMAC (RHUS CORIARIA L.) PHENOLIC EXTRACT ON THE GROWTH OF PATHOGENIC BACTERIA

Basit Öğe Kaydı
dc.contributor.authorIlk, Sedef
dc.date.accessioned2024-11-07T13:25:16Z
dc.date.available2024-11-07T13:25:16Z
dc.date.issued2019
dc.departmentNiğde Ömer Halisdemir Üniversitesi
dc.description.abstractPlant secondary metabolites are phenolic compounds which have many bioactivities such as antioxidant, antimicrobial and also inhibition of quorum sensing-regulated violacein pigment production properties. The objective of this study was to determine the antioxidant, antimicrobial activity and quorum sensing inhibition (QSI) activity by the three phenolic extract (water, ethanol and acetone) of the fruits of three different wildly grown sumac (Rhus coriaria L.) genotypes from Diyarbakir region of Turkey. The phenolic content of extract was determined as within range 152,07 +/- 7,5- 452,4 +/- 17,6 mu g GAE g dw(-1). The antioxidant activity determined through the ABTS(+) method was ranged from 17,89 +/- 0,92 to 41,75 +/- 1,11 mu mol TE/g dw. The all of the tested phenolic extracts were able to inhibit all the evaluated bacteria by the disc diffusion assay in the range of 6.29 +/- 0.71-27.84 +/- 1.42 mm and inhibited the quorum sensing phenomena in bacteria within ranges from 16.27 +/- 0.59 to 24.78 +/- 0.68 mm, among them, for the activity, the ethanoic extraction was the most effective solvent system for Rhus coriaria phenolic bioactivity. The sumac phenolic extract exhibited high antioxidant capacity, antimicrobial and anti-quorum sensing properties. To our knowledge, this is the first report on the QSI activity of sumac fruit extract. The discovery of nontoxic novel compounds within antibacterial and QSI activity could lead to the development of antimicrobial therapeutic agents that can be alternative and complementary treatments against antibiotic resistant pathogenic bacteria.
dc.identifier.endpage7745
dc.identifier.issn1018-4619
dc.identifier.issn1610-2304
dc.identifier.issue11
dc.identifier.startpage7739
dc.identifier.urihttps://hdl.handle.net/11480/14614
dc.identifier.volume28
dc.identifier.wosWOS:000492801100008
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.language.isoen
dc.publisherParlar Scientific Publications (P S P)
dc.relation.ispartofFresenius Environmental Bulletin
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241106
dc.subjectRhus coriaria L.
dc.subjectphenolic extracts
dc.subjectantioxidant activity
dc.subjectquorum sensing inhibition
dc.subjectantimicrobial activity
dc.titleQUORUM SENSING INHIBITION AND ANTIMICROBIAL EFFECT OF SUMAC (RHUS CORIARIA L.) PHENOLIC EXTRACT ON THE GROWTH OF PATHOGENIC BACTERIA
dc.typeArticle

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu