Comparison of Preoperative and Postoperative Antioxidant Levels in Patients with Adenotonsillar Hypertrophy

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dc.contributor.authorEkinci, Adnan
dc.contributor.authorDağıstan, Hakan
dc.contributor.authorAksoy, Ahmet
dc.contributor.authorEkinci, Halil
dc.date.accessioned2024-11-07T10:40:17Z
dc.date.available2024-11-07T10:40:17Z
dc.date.issued2020
dc.departmentNiğde Ömer Halisdemir Üniversitesi
dc.description.abstractObjective: This study aimed to compare the serum oxidative stress levels of patients with adenotonsillar hypertrophy (ATH) with those of controls and to investigate the effects of adenotonsillectomy on the oxidative stress levels. Material and Methods: Thirty healthy children (mean age, 6 years) and 30 patients with ATH (mean age, 7 years) aged 2-12 years were included in the study. Serum total oxidant status (TOS), total antioxidant status (TAS), oxidative stress index (OSI), and paraoxonase (PON) levels were compared between the patient and control groups. The preoperative and postoperative levels were also compared within the patient group. Results: The TOS and OSI levels were significantly higher in the patient group than in the control group (p=0.007 and p=0.027, respectively). There was no significant difference between the patient and control groups in terms of the TAS and PON levels (p=0.399 and p=0.237, respectively). The TOS and OSI levels in the patient group were significantly higher in the preoperative than in the postoperative period (p=0.005 and p=0.023, respectively), whereas there were no significant differences in the TAS and PON levels between the preoperative and postoperative period (p=0.192 and p=0.262, respectively). Conclusion: These findings demonstrate that patients with ATH are exposed to high levels of oxidative stress and that adenotonsillectomy normalizes the oxidative stress. © 2020, AVES. All rights reserved.
dc.identifier.doi10.5152/ejra.2020.297
dc.identifier.endpage38
dc.identifier.issn2636-8072
dc.identifier.issue2
dc.identifier.scopus2-s2.0-85123223882
dc.identifier.scopusqualityN/A
dc.identifier.startpage34
dc.identifier.trdizinid381761
dc.identifier.urihttps://doi.org/10.5152/ejra.2020.297
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/381761
dc.identifier.urihttps://hdl.handle.net/11480/11549
dc.identifier.volume3
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherAVES
dc.relation.ispartofEuropean Journal of Rhinology and Allergy
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241106
dc.subjectAdenotonsillar hypertrophy
dc.subjectoxidative stress ındex
dc.subjectparaoxo-nase
dc.subjecttotal antioxidant status
dc.subjecttotal oxidant status
dc.titleComparison of Preoperative and Postoperative Antioxidant Levels in Patients with Adenotonsillar Hypertrophy
dc.typeArticle

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