Effect of Sugammadex on Coagulation Parameters in Cesarean Section Patients a Prospective Controlled Observational Study

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dc.contributor.authorDestegul, Emre
dc.contributor.authorDestegul, Dilek
dc.contributor.authorKocaoz, Fazilet
dc.date.accessioned2024-11-07T13:24:45Z
dc.date.available2024-11-07T13:24:45Z
dc.date.issued2021
dc.departmentNiğde Ömer Halisdemir Üniversitesi
dc.description.abstractObjective: To evaluate, for the first time in the literature, the effect of sugammadex in elective C/S patients in terms of hemostatic parameters and postoperative bleeding. Methods: Seventy-six patients enrolled for this observational prospective controlled study. Patients were divided into two groups according to anesthetic reversal agent: sugammadex (group I) vs neostigmin (group II). Intraoperative and postoperative amount of bleeding were recorded. At the end of the surgery, after administration of reversal agent, and at postoperative 30th minute, 1st, and 2nd hours, activated partial thromboplastin time (aPTT), prothrombin time (PT), and international normalized ratio (INR) values were recorded. Postoperative Hct, Hgb, and Plt values at 6th and 24th hours of reversal agent administration were also recorded. Results: Alterations in aPTT, PT, and INR values were similar between the groups (P = .986, .549, .05, respectively). Conclusion: Sugammadex at 2 mg kg(-1) in cesarean section patients has a similar effect on coagulation parameters compared to neostigmin. Further studies are needed particularly in patients under thromboprophylaxis.
dc.identifier.doi10.5152/eurjther.2021.21003
dc.identifier.endpage298
dc.identifier.issn2564-7040
dc.identifier.issue4
dc.identifier.startpage293
dc.identifier.trdizinid503287
dc.identifier.urihttps://doi.org/10.5152/eurjther.2021.21003
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/503287
dc.identifier.urihttps://hdl.handle.net/11480/14286
dc.identifier.volume27
dc.identifier.wosWOS:000743972800008
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherAves
dc.relation.ispartofEuropean Journal of Therapeutics
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241106
dc.subjectCesarean section
dc.subjectcoagulation
dc.subjectsugammadex
dc.subjectaPTT
dc.subjectneostigmin
dc.subjectpostpartum bleeding
dc.titleEffect of Sugammadex on Coagulation Parameters in Cesarean Section Patients a Prospective Controlled Observational Study
dc.typeArticle

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