Bioactivity of Hawthorn (Crataegus monogyna) and Heather (Calluna vulgaris) Leaf Tinctures: An Optimization Study Using Response Surface Methodology

Basit Öğe Kaydı
dc.contributor.authorKaraman, Safa
dc.date.accessioned2024-11-07T13:16:17Z
dc.date.available2024-11-07T13:16:17Z
dc.date.issued2023
dc.departmentNiğde Ömer Halisdemir Üniversitesi
dc.description.abstractIn the current research, two medicinal important plants namely hawthorn (Crataegus monogyna) and heather (Calluna vulgaris) leaf were used for the tincture production according to central composite rotatable design and the produced tinctures were subjected to bioactive analysis to reveal the optimum manufacturing conditions. As response, total phenolic content and radical scavenging performance of the produced tinctures were analyzed. The levels of total phenolics and radical scavenging performance activity of the hawthorn and heather tinctures ranged between 2996.9-5415.8 mg GAE/L and 5514.9-13923.6 mg GAE/L and 26.9-71.9 and 51.0-94.1%, respectively. Effect of both liquid/solid ratio and ethanol concentration affected the bioactivity of the samples. Optimization process revealed that the optimum levels for the highest total phenolic content and antiradical activity were 4.03 mL/g for liquid/solid ratio and 67.07% for ethanol level for the hawthorn tincture and 4.03 mL/g for liquid/solid ratio and 53.77% for ethanol level for the heather tincture. The results of the current work revealed that the processing variables had important effect on the bioactivity of the tinctures.
dc.identifier.doi10.21597/jist.1175955
dc.identifier.endpage325
dc.identifier.issn2146-0574
dc.identifier.issn2536-4618
dc.identifier.issue1
dc.identifier.startpage317
dc.identifier.trdizinid1160186
dc.identifier.urihttps://doi.org/10.21597/jist.1175955
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1160186
dc.identifier.urihttps://hdl.handle.net/11480/12187
dc.identifier.volume13
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofIğdır Üniversitesi Fen Bilimleri Enstitüsü Dergisi
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241107
dc.subjectTamamlayıcı ve Entegre Tıp
dc.subjectBiyoloji
dc.subjectBahçe Bitkileri
dc.subjectKimya
dc.subjectTıbbi
dc.subjectGıda Bilimi ve Teknolojisi
dc.subjectVeterinerlik
dc.subjectBitki Bilimleri
dc.subjectOptimization
dc.subjectbioactivity
dc.subjecttincture
dc.titleBioactivity of Hawthorn (Crataegus monogyna) and Heather (Calluna vulgaris) Leaf Tinctures: An Optimization Study Using Response Surface Methodology
dc.typeArticle

Dosyalar

Koleksiyon

TR-Dizin İndeksli Yayınlar Koleksiyonu