Comparison Of The Relationship Between Inflammatory Markers And Saphenous Vein Graft Disease In Patients With Stable Angina Pectoris

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Tarih

2023

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Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

Aim: Coronary artery bypass graft surgery is one of the most commonly used strategies to revascularization of occlusive coronary atherosclerotic lesions. Atherosclerosis is known to be a chronic inflammatory process. Many inflammatory cells and mechanisms are active in this process. Markers such as mean platelet volume-to-lymphocyte ratio (MPVLR) and C-reactive protein-to-albumin (CAR) which may be associated with the severity of inflammation. In this study, it was aimed to determine the relationship between these parameters and saphenous vein graft (SVG) diseases. Methods: In this retrospective study, 314 patients SVG disease with stable angina pectoris were included. Patients were divided into two groups according to the severity of SVG disease. We compared 159 patients who had severe stenosis in SVG and 156 patients who did not,in terms of CAR, NLR, PLR, MPVLR. Results: Patients who ?50% stenosis in SVG had significantly higher CAR, MPVLR, NLR, and PLR (respectively 9.1 (4.2-16.8) p<0.001, 4.5)0.68) p<0.001, 2.4 (0.69) p=0.002, 153 )6) p=0.048). In line with these data, CAR and MPVLR values were also higher in the group with ?50% stenosis in SVG, which was highly statistically significant (respectively 3.2 (0.9-4.4) vs 9.1 (4.2-16.8); p<0.001 and 3.64)0.43) vs 4.53)0.68); p<0.001). Conclusion: C-reactive protein-to-albumin and MPVLR can be a useful and easily accessible markers to predict severity SVG stenosis.

Açıklama

Anahtar Kelimeler

Tıbbi İnformatik, Onkoloji, Kalp ve Kalp Damar Sistemi, Neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, C-reactive protein-to-albumin, mean platelet volume-to-lymphocytes ratio, saphenous vein graft diseases.

Kaynak

Acta Medica Alanya

WoS Q Değeri

Scopus Q Değeri

Cilt

7

Sayı

3

Künye